PFN4

Gene Symbol PFN4
Entrez Gene 375189
Alt Symbol -
Species Human
Gene Type protein-coding
Description profilin family, member 4
Other Description profilin IV|profilin-4
Swissprots Q53TL9 Q8NHR9
Accessions AAY14666 EAX00760 EAX00761 Q8NHR9 AK292601 BAF85290 BC029523 AAH29523 BC043236 XM_005264292 XP_005264349 XM_006712007 XP_006712070 XM_011532823 XP_011531125 XM_011532824 XP_011531126 NM_199346 NP_955378
Function Binds to phosphatidylinositol 3-phosphate (PtdIns(3)P), phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)P2), phosphatidylinositol 4-phosphate (PtdIns(4)P) and phosphatidic acid (PA). Does not bind to actin (PubMed:19419568), contrary to other family members. {ECO:0000269|PubMed:19419568}.
Subcellular Location Cytoplasm, cytoskeleton {ECO:0000250}.
Tissue Specificity Detected in testis (at protein level). {ECO:0000269|PubMed:15591451}.
Top Pathways Salmonella infection, Rap1 signaling pathway, Regulation of actin cytoskeleton

Profilin-4 CRISPR/Cas9 KO Plasmid (h) - sc-415706 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Profilin-4 HDR Plasmid (h) - sc-415706-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Profilin-4 Double Nickase Plasmid (h) - sc-415706-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Profilin-4 Double Nickase Plasmid (h2) - sc-415706-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Profilin-4 CRISPR Activation Plasmid (h) - sc-415706-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Profilin-4 CRISPR Activation Plasmid (h2) - sc-415706-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Profilin-4 Lentiviral Activation Particles (h) - sc-415706-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Profilin-4 Lentiviral Activation Particles (h2) - sc-415706-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Profilin-4 siRNA (h) - sc-94769 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Profilin-4 shRNA Plasmid (h) - sc-94769-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Profilin-4 shRNA (h) Lentiviral Particles - sc-94769-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MISSION® esiRNA - EHU040101 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN16664 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND16664 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR00671 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr00671

PFN4 siRNA (Human) - CRJ7657 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human PFN4 (NM_199346.1) - SHH374028 from Creative biogene

Category siRNA
Species Reactivities Human

shRNA set against Human PFN4(NM_199346.1) - SHR108168 from Creative biogene

Category siRNA
Species Reactivities Human

Human PFN4 siRNA - orb278158 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

PFN4 shRNA Plasmid (Human) - CHJ7657 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

PFN4 miRNA 3'UTR clone - MiUTR1H-07808 from Creative biogene

Species Reactivities Human
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