Gene Symbol | ANAPC13 |
---|---|
Entrez Gene | 25847 |
Alt Symbol | APC13, SWM1 |
Species | Human |
Gene Type | protein-coding |
Description | anaphase promoting complex subunit 13 |
Other Description | anaphase-promoting complex subunit 13|cyclosome subunit 13 |
Swissprots | Q9BS18 Q9Y3V0 |
Accessions | EAW79143 EAW79144 EAW79145 EAW79146 EAW79147 EAW79148 EAW79149 Q9BS18 AF086169 AK001285 AK026550 AK290761 BAF83450 AL050051 CAB43251 AV682398 BC005398 AAH05398 BG428689 BU627217 BU852706 BX537696 CN258858 NM_001242374 NP_001229303 NM_001242375 NP_001229304 NM_015391 NP_056206 |
Function | Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains. {ECO:0000269|PubMed:15060174, ECO:0000269|PubMed:18485873}. |
Subcellular Location | Nucleus {ECO:0000305}. |
Top Pathways | Cell cycle, Ubiquitin mediated proteolysis, Progesterone-mediated oocyte maturation, Oocyte meiosis |
APC13 CRISPR/Cas9 KO Plasmid (h) - sc-417758 from Santa Cruz Biotechnology
|
||||||||
APC13 HDR Plasmid (h) - sc-417758-HDR from Santa Cruz Biotechnology
|
||||||||
APC13 Double Nickase Plasmid (h) - sc-417758-NIC from Santa Cruz Biotechnology
|
||||||||
APC13 Double Nickase Plasmid (h2) - sc-417758-NIC-2 from Santa Cruz Biotechnology
|
||||||||
APC13 CRISPR Activation Plasmid (h) - sc-417758-ACT from Santa Cruz Biotechnology
|
||||||||
APC13 CRISPR Activation Plasmid (h2) - sc-417758-ACT-2 from Santa Cruz Biotechnology
|
||||||||
APC13 Lentiviral Activation Particles (h) - sc-417758-LAC from Santa Cruz Biotechnology
|
||||||||
APC13 Lentiviral Activation Particles (h2) - sc-417758-LAC-2 from Santa Cruz Biotechnology
|
||||||||
APC13 siRNA (h) - sc-78311 from Santa Cruz Biotechnology
|
||||||||
APC13 shRNA Plasmid (h) - sc-78311-SH from Santa Cruz Biotechnology
|
||||||||
APC13 shRNA (h) Lentiviral Particles - sc-78311-V from Santa Cruz Biotechnology
|
||||||||
MISSION® esiRNA - EHU088181 from Sigma-Aldrich
|
||||||||
CompoZr® Knockout ZFN Kit - CKOZFN3138 from Sigma-Aldrich
|
||||||||
CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND3138 from Sigma-Aldrich
|
||||||||
MISSION® 3′UTR Lenti GoClone™ - HUTR06556 from Sigma-Aldrich
|
||||||||
ANAPC13 siRNA (Human) - CRH8540 from Cohesion Biosciences
|
||||||||
ANAPC13 - MBS8236442 from MyBioSource
|
||||||||
shRNA set against Human ANAPC13 (NM_015391.3) - SHH236098 from Creative biogene
|
||||||||
ANAPC13 shRNA Plasmid (Human) - CHH8540 from Cohesion Biosciences
|
||||||||
ANAPC13 miRNA 3'UTR clone - MiUTR3H-13270 from Creative biogene
|