| Gene Symbol |
APOA4
|
| Entrez Gene |
337
|
| Alt Symbol |
-
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
apolipoprotein A-IV
|
| Other Description |
apo-AIV|apoA-IV|apolipoprotein A4
|
| Swissprots |
P06727 A8MSL6 Q14CW8 Q6Q787
|
| Accessions |
AAA51745 AAA96731 AAQ91809 AAS68228 EAW67271 P06727 AL531739 BC074764 AAH74764 BC113594 AAI13595 BC113596 AAI13597 HQ258218 ADR82972 HQ258399 ADR83153 M10373 AAB59516 M13654 AAA51744 M14566 AAA51748 X13629 CAA31955 NM_000482 NP_000473
|
| Function |
May have a role in chylomicrons and VLDL secretion and catabolism. Required for efficient activation of lipoprotein lipase by ApoC-II; potent activator of LCAT. Apoa-IV is a major component of HDL and chylomicrons.
|
| Subcellular Location |
Secreted.
|
| Tissue Specificity |
Synthesized primarily in the intestine and secreted in plasma.
|
| Top Pathways |
Fat digestion and absorption, Vitamin digestion and absorption
|
![Western Blot: Apolipoprotein A-IV/ApoA4 Overexpression Lysate (Denatured) [H00000337-T01] - Lane 1: APOA4 transfected lysate (45.4 KDa) Lane 2: Non-transfected lysate.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_1/26660_Apolipoprotein-A-IV-ApoA4-Overexpression-Lysate-(Denatured)-Western-Blot-H00000337-T01-img0002.jpg)
![Western Blot: APOA4 Overexpression Lysate (Adult Normal) [NBP2-09022] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for APOA4.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/2330_APOA4%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBP2-09022-img0001.jpg)