Gene Symbol | APOA4 |
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Entrez Gene | 337 |
Alt Symbol | - |
Species | Human |
Gene Type | protein-coding |
Description | apolipoprotein A-IV |
Other Description | apo-AIV|apoA-IV|apolipoprotein A4 |
Swissprots | P06727 A8MSL6 Q14CW8 Q6Q787 |
Accessions | AAA51745 AAA96731 AAQ91809 AAS68228 EAW67271 P06727 AL531739 BC074764 AAH74764 BC113594 AAI13595 BC113596 AAI13597 HQ258218 ADR82972 HQ258399 ADR83153 M10373 AAB59516 M13654 AAA51744 M14566 AAA51748 X13629 CAA31955 NM_000482 NP_000473 |
Function | May have a role in chylomicrons and VLDL secretion and catabolism. Required for efficient activation of lipoprotein lipase by ApoC-II; potent activator of LCAT. Apoa-IV is a major component of HDL and chylomicrons. |
Subcellular Location | Secreted. |
Tissue Specificity | Synthesized primarily in the intestine and secreted in plasma. |
Top Pathways | Fat digestion and absorption, Vitamin digestion and absorption |
apoA-IV CRISPR/Cas9 KO Plasmid (h) - sc-402217 from Santa Cruz Biotechnology
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apoA-IV HDR Plasmid (h) - sc-402217-HDR from Santa Cruz Biotechnology
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apoA-IV Double Nickase Plasmid (h) - sc-402217-NIC from Santa Cruz Biotechnology
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apoA-IV Double Nickase Plasmid (h2) - sc-402217-NIC-2 from Santa Cruz Biotechnology
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apoA-IV CRISPR Activation Plasmid (h) - sc-402217-ACT from Santa Cruz Biotechnology
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apoA-IV CRISPR Activation Plasmid (h2) - sc-402217-ACT-2 from Santa Cruz Biotechnology
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apoA-IV Lentiviral Activation Particles (h) - sc-402217-LAC from Santa Cruz Biotechnology
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apoA-IV Lentiviral Activation Particles (h2) - sc-402217-LAC-2 from Santa Cruz Biotechnology
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apoA-IV siRNA (h) - sc-41178 from Santa Cruz Biotechnology
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apoA-IV shRNA Plasmid (h) - sc-41178-SH from Santa Cruz Biotechnology
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apoA-IV shRNA (h) Lentiviral Particles - sc-41178-V from Santa Cruz Biotechnology
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Apolipoprotein A-IV/ApoA4 RNAi - H00000337-R01 from Novus Biologicals
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MISSION® esiRNA - EHU107901 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN3329 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND3329 from Sigma-Aldrich
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shRNA set against Human APOA4 (NM_000482.3) - SHH238354 from Creative biogene
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shRNA set against Human APOA4(NM_000482.3) - SHG065251 from Creative biogene
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APOA4 miRNA 3'UTR clone - MiUTR4H-TG10586 from Creative biogene
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