Gene Symbol |
TOE1
|
Entrez Gene |
114034
|
Alt Symbol |
-
|
Species |
Human
|
Gene Type |
protein-coding
|
Description |
target of EGR1, member 1 (nuclear)
|
Other Description |
target of EGR1 protein 1
|
Swissprots |
Q8IWN5 Q9H846 B4DEM6 Q96GM8 Q6IA35
|
Accessions |
EAX06990 Q96GM8 AK024011 BAB14774 AK093320 BAG52689 AK293704 BAG57137 AK298162 BAG60435 AY169960 AAN75441 BC009364 AAH09364 BI495405 CR457320 CAG33601 DA887065 JF432181 ADZ15398 XM_005270412 XP_005270469 XM_005270413 XP_005270470 XM_011540569 XP_011538871 XR_246230 XR_426587 XR_946532 NM_025077 NP_079353
|
Function |
Inhibits cell growth rate and cell cycle. Induces CDKN1A expression as well as TGF-beta expression. Mediates the inhibitory growth effect of EGR1. {ECO:0000269|PubMed:12562764}.
|
Subcellular Location |
Nucleus, nucleolus {ECO:0000269|PubMed:12562764}. Nucleus speckle {ECO:0000269|PubMed:12562764}. Note=Localizes to nuclear speckles.
|