Gene Symbol | TOE1 |
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Entrez Gene | 114034 |
Alt Symbol | - |
Species | Human |
Gene Type | protein-coding |
Description | target of EGR1, member 1 (nuclear) |
Other Description | target of EGR1 protein 1 |
Swissprots | Q8IWN5 Q9H846 B4DEM6 Q96GM8 Q6IA35 |
Accessions | EAX06990 Q96GM8 AK024011 BAB14774 AK093320 BAG52689 AK293704 BAG57137 AK298162 BAG60435 AY169960 AAN75441 BC009364 AAH09364 BI495405 CR457320 CAG33601 DA887065 JF432181 ADZ15398 XM_005270412 XP_005270469 XM_005270413 XP_005270470 XM_011540569 XP_011538871 XR_246230 XR_426587 XR_946532 NM_025077 NP_079353 |
Function | Inhibits cell growth rate and cell cycle. Induces CDKN1A expression as well as TGF-beta expression. Mediates the inhibitory growth effect of EGR1. {ECO:0000269|PubMed:12562764}. |
Subcellular Location | Nucleus, nucleolus {ECO:0000269|PubMed:12562764}. Nucleus speckle {ECO:0000269|PubMed:12562764}. Note=Localizes to nuclear speckles. |
TOE1 CRISPR/Cas9 KO Plasmid (h) - sc-409131 from Santa Cruz Biotechnology
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TOE1 HDR Plasmid (h) - sc-409131-HDR from Santa Cruz Biotechnology
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TOE1 Double Nickase Plasmid (h) - sc-409131-NIC from Santa Cruz Biotechnology
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TOE1 Double Nickase Plasmid (h2) - sc-409131-NIC-2 from Santa Cruz Biotechnology
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TOE1 CRISPR Activation Plasmid (h) - sc-409131-ACT from Santa Cruz Biotechnology
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TOE1 CRISPR Activation Plasmid (h2) - sc-409131-ACT-2 from Santa Cruz Biotechnology
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TOE1 Lentiviral Activation Particles (h) - sc-409131-LAC from Santa Cruz Biotechnology
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TOE1 Lentiviral Activation Particles (h2) - sc-409131-LAC-2 from Santa Cruz Biotechnology
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TOE1 siRNA (h) - sc-88412 from Santa Cruz Biotechnology
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TOE1 shRNA Plasmid (h) - sc-88412-SH from Santa Cruz Biotechnology
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TOE1 shRNA (h) Lentiviral Particles - sc-88412-V from Santa Cruz Biotechnology
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TOE1 RNAi - H00114034-R01V from Novus Biologicals
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TOE1 RNAi - H00114034-R01 from Novus Biologicals
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MISSION® esiRNA - EHU153351 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN21807 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND21807 from Sigma-Aldrich
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TOE1 siRNA (Human) - CRJ4346 from Cohesion Biosciences
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TOE1 - MBS8232464 from MyBioSource
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shRNA set against Human TOE1 (NM_025077.3) - SHH432648 from Creative biogene
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shRNA set against Human TOE1(NM_025077.3) - SHH223546 from Creative biogene
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Human TOE1 siRNA - orb274847 from Biorbyt
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TOE1 shRNA Plasmid (Human) - CHJ4346 from Cohesion Biosciences
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TOE1 miRNA 3'UTR clone - MiUTR1H-10636 from Creative biogene
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