OSBPL1A

Gene Symbol OSBPL1A
Entrez Gene 114876
Alt Symbol ORP-1, ORP1, OSBPL1B
Species Human
Gene Type protein-coding
Description oxysterol binding protein-like 1A
Other Description OSBP-related protein 1|oxysterol binding protein-like 1B|oxysterol-binding protein-related protein 1|oxysterol-binding protein-related protein 1 variant 1|oxysterol-binding protein-related protein 1 variant 2
Swissprots B7Z7D3 Q9NW87 Q9BZF5 Q9BXW6
Accessions ACA06034 ACA06035 EAX01180 EAX01181 EAX01182 EAX01183 Q9BXW6 AF274714 AAK15154 AF323726 AAG53407 AF392449 AAL40662 AF392450 AAL40663 AK001079 AK021898 AK096358 BAG53273 AK292895 BAF85584 AK301862 BAH13569 AK314552 BAG37138 BC007004 AAH07004 BC022293 BC041563 AAH41563 BC063420 AAH63420 BC073854 AAH73854 BC098384 AAH98384 BC136452 AAI36453 BC144117 AAI44118 BX647893 XM_006722380 XP_006722443 XM_006722381 XP_006722444 XM_006722382 XP_006722445 XM_006722383 XP_006722446 XM_011525800 XP_011524102 XR_935193 NM_001242508 NP_001229437 NM_018030 NP_060500 NM_080597 NP_542164 NM_133268
Function Binds phospholipids; exhibits strong binding to phosphatidic acid and weak binding to phosphatidylinositol 3- phosphate (By similarity). Stabilizes GTP-bound RAB7A on late endosomes/lysosomes and alters functional properties of late endocytic compartments via its interaction with RAB7A. {ECO:0000250, ECO:0000269|PubMed:16176980}.
Subcellular Location Late endosome {ECO:0000269|PubMed:16176980}. Note=Colocalizes with RAB7A, RAB9A and LAMP1 in late endosomes.

ORP-1 (B-3) - sc-376602 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
ORP-1 (B-3): sc-376602. Western blot analysis of ORP-1 expression in mouse heart (A) and human skeletal muscle (B) tissue extracts.

ORP-1 (H-53) - sc-135104 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal

ORP-1 (E-14) - sc-66491 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

ORP-1 (C-19) - sc-66490 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
ORP-1 (C-19): sc-66490. Western blot analysis of ORP-1 expression in mouse heart tissue extract.

Anti-ORP1 antibody - ab203352 from Abcam

Prices $359.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Anti-ORP1 antibody (ab203352) at 1/300 dilution (at 4°C) + Mouse brain lysateSecondaryGoat Anti-Rabbit IgG Antibody (H+L), HRP Conjugated (90min in 37°C) at 1/5000 dilution

Anti-ORP1 antibody - ab96522 from Abcam

Prices $359.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Anti-ORP1 antibody (ab96522) at 1/1000 dilution + H1299 whole cell lysate at 30 µg

Anti-ORP1 antibody - ab10151 from Abcam

Prices $370.00
Sizes 100 µg
Host Goat
Clonality Polyclonal

Anti-ORP1 antibody - ab130369 from Abcam

Prices $370.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Anti-ORP1 antibody (ab130369) at 1/100 dilution + HeLa cell line lysates at 35 µg

Anti-ORP1 antibody [EPR8646] - ab131165 from Abcam

Prices $313.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR8646
All lanes : Anti-ORP1 antibody [EPR8646] (ab131165) at 1/1000 dilutionLane 1 : A549 cell lysateLane 2 : 293T cell lysateLane 3 : U87-MG cell lysateLysates/proteins at 10 µg per lane.SecondaryHRP labelled goat anti-rabbit IgG at 1/2000 dilution

Anti-OSBPL1A / ORP1 Antibody (aa503-552) - LS-C111054 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
OSBPL1A / ORP1 antibody LS-C111054 Western blot of Fetal Small Intestine lysate.

Anti-OSBPL1A / ORP1 Antibody (aa736-763) - LS-C163276 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
OSBPL1A Antibody western blot of HeLa cell line lysates (35 ug/lane). The OSBPL1A antibody detected the OSBPL1A protein (arrow).

Anti-OSBPL1A / ORP1 Antibody (C-Terminus, clone EPR8646) - LS-C154581 from LifeSpan Bioscience

Prices $395.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR8646
Western blot analysis on (A) A549, (B) 293T, and (C) U87-MG cell lysates using anti-OSBPL1A / ORP1 antibody.

Anti-OSBPL1A / ORP1 Antibody (aa938-950) IHC-plus™ - LS-B4811 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Goat
Clonality Polyclonal
Anti-OSBPL1A / ORP1 antibody IHC of human skeletal muscle. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B4811 concentration 5 ug/ml.

Anti-OSBPL1A / ORP1 Antibody (aa888-950) - LS-C185905 from LifeSpan Bioscience

Prices $335.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
IHC of paraffin-embedded A549 xenograft using ORP1 antibody at 1:100 dilution.

Anti-OSBPL1A / ORP1 Antibody (aa736-763, AP) - LS-C265251 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-OSBPL1A / ORP1 Antibody (aa736-763, APC) - LS-C265252 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-OSBPL1A / ORP1 Antibody (aa736-763, FITC) - LS-C265254 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-OSBPL1A / ORP1 Antibody (aa736-763, Biotin) - LS-C265253 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-OSBPL1A / ORP1 Antibody (aa736-763, Azide-free, HRP) - LS-C265255 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-OSBPL1A / ORP1 Antibody (aa736-763, PE) - LS-C265257 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-OSBPL1A / ORP1 Antibody (aa734-763) - LS-C323695 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

ORP1 Antibody - NB100-1331 from Novus Biologicals

Prices $299.00
Sizes 100 µg
Host Goat
Clonality Polyclonal
Western Blot: ORP1 Antibody [NB100-1331] - (0.5ug/ml) of Human Muscle lysate (RIPA buffer, 35ug total protein per lane). Primary incubated for 1 hour. Detected by chemiluminescence.

ORP1 Antibody - NBP1-92234 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunocytochemistry/Immunofluorescence: ORP1 Antibody [NBP1-92234] - Staining of human cell line A-431 shows positivity in nucleus but not nucleoli & cytoplasm.

ORP1 Antibody - NBP1-92233 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemistry-Paraffin: ORP1 Antibody [NBP1-92233] - Staining of human cerebellum shows strong cytoplasmic and nuclear positivity in Purkinje cells.

ORP1 Polyclonal Antibody - bs-17514R from Bioss

Prices $269.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Formalin-fixed and paraffin embedded rat testies labeled with Rabbit Anti-ORP1 Polyclonal Antibody, Unconjugated (bs-17514R) at 1:200 followed by conjugation to the secondary antibody and DAB staining
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