| Gene Symbol | Glul |
|---|---|
| Entrez Gene | 14645 |
| Alt Symbol | GS, Glns |
| Species | Mouse |
| Gene Type | protein-coding |
| Description | glutamate-ammonia ligase (glutamine synthetase) |
| Other Description | glutamate decarboxylase|glutamate-ammonia ligase (glutamine synthase)|glutamine synthetase |
| Swissprots | Q3TRK7 Q91VC6 P15105 Q64432 |
| Accessions | P15105 AK137969 AK146463 AK152497 AK158643 AK159106 BAE34822 AK159888 AK160670 BAE35950 AK162685 BAE37022 AK168493 BAE40380 AY044241 AAK95328 BC015086 AAH15086 BE946110 U09114 AAA17989 X16314 CAA34381 NM_008131 NP_032157 |
| Function | Essential for proliferation of fetal skin fibroblasts. This enzyme has 2 functions: it catalyzes the production of glutamine and 4-aminobutanoate (gamma-aminobutyric acid, GABA), the latter in a pyridoxal phosphate-independent manner (By similarity). {ECO:0000250}. |
| Subcellular Location | Cytoplasm. Mitochondrion {ECO:0000250}. |
| Top Pathways | Nitrogen metabolism, GABAergic synapse, Glutamatergic synapse, Arginine and proline metabolism, Glyoxylate and dicarboxylate metabolism |