Gene Symbol |
Glul
|
Entrez Gene |
14645
|
Alt Symbol |
GS, Glns
|
Species |
Mouse
|
Gene Type |
protein-coding
|
Description |
glutamate-ammonia ligase (glutamine synthetase)
|
Other Description |
glutamate decarboxylase|glutamate-ammonia ligase (glutamine synthase)|glutamine synthetase
|
Swissprots |
Q3TRK7 Q91VC6 P15105 Q64432
|
Accessions |
P15105 AK137969 AK146463 AK152497 AK158643 AK159106 BAE34822 AK159888 AK160670 BAE35950 AK162685 BAE37022 AK168493 BAE40380 AY044241 AAK95328 BC015086 AAH15086 BE946110 U09114 AAA17989 X16314 CAA34381 NM_008131 NP_032157
|
Function |
Essential for proliferation of fetal skin fibroblasts. This enzyme has 2 functions: it catalyzes the production of glutamine and 4-aminobutanoate (gamma-aminobutyric acid, GABA), the latter in a pyridoxal phosphate-independent manner (By similarity). {ECO:0000250}.
|
Subcellular Location |
Cytoplasm. Mitochondrion {ECO:0000250}.
|
Top Pathways |
Nitrogen metabolism, GABAergic synapse, Glutamatergic synapse, Arginine and proline metabolism, Glyoxylate and dicarboxylate metabolism
|