Gene Symbol | Glul |
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Entrez Gene | 14645 |
Alt Symbol | GS, Glns |
Species | Mouse |
Gene Type | protein-coding |
Description | glutamate-ammonia ligase (glutamine synthetase) |
Other Description | glutamate decarboxylase|glutamate-ammonia ligase (glutamine synthase)|glutamine synthetase |
Swissprots | Q3TRK7 Q91VC6 P15105 Q64432 |
Accessions | P15105 AK137969 AK146463 AK152497 AK158643 AK159106 BAE34822 AK159888 AK160670 BAE35950 AK162685 BAE37022 AK168493 BAE40380 AY044241 AAK95328 BC015086 AAH15086 BE946110 U09114 AAA17989 X16314 CAA34381 NM_008131 NP_032157 |
Function | Essential for proliferation of fetal skin fibroblasts. This enzyme has 2 functions: it catalyzes the production of glutamine and 4-aminobutanoate (gamma-aminobutyric acid, GABA), the latter in a pyridoxal phosphate-independent manner (By similarity). {ECO:0000250}. |
Subcellular Location | Cytoplasm. Mitochondrion {ECO:0000250}. |
Top Pathways | Nitrogen metabolism, GABAergic synapse, Glutamatergic synapse, Arginine and proline metabolism, Glyoxylate and dicarboxylate metabolism |
Gl Syn CRISPR/Cas9 KO Plasmid (m) - sc-420579 from Santa Cruz Biotechnology
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Gl Syn HDR Plasmid (m) - sc-420579-HDR from Santa Cruz Biotechnology
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Gl Syn Double Nickase Plasmid (m) - sc-420579-NIC from Santa Cruz Biotechnology
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Gl Syn Double Nickase Plasmid (m2) - sc-420579-NIC-2 from Santa Cruz Biotechnology
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Gl Syn CRISPR Activation Plasmid (m) - sc-420579-ACT from Santa Cruz Biotechnology
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Gl Syn CRISPR Activation Plasmid (m2) - sc-420579-ACT-2 from Santa Cruz Biotechnology
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Gl Syn Lentiviral Activation Particles (m) - sc-420579-LAC from Santa Cruz Biotechnology
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Gl Syn Lentiviral Activation Particles (m2) - sc-420579-LAC-2 from Santa Cruz Biotechnology
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Gl Syn siRNA (m) - sc-35482 from Santa Cruz Biotechnology
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Gl Syn shRNA Plasmid (m) - sc-35482-SH from Santa Cruz Biotechnology
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Gl Syn shRNA (m) Lentiviral Particles - sc-35482-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EMU064131 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN31973 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND31973 from Sigma-Aldrich
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GLUL siRNA (Mouse) - CRM1584 from Cohesion Biosciences
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GLUL - MBS8200962 from MyBioSource
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shRNA set against Mouse Glul(NM_008131.3) - SHH088589 from Creative biogene
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Mouse GLUL siRNA - orb281060 from Biorbyt
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GLUL shRNA Plasmid (Mouse) - CHM1584 from Cohesion Biosciences
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GLUL miRNA 3'UTR clone - MiUTR1M-05097 from Creative biogene
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