Dmp1

Gene Symbol	Dmp1
Entrez Gene	25312
Alt Symbol	DENTMAT
Species	Rat
Gene Type	protein-coding
Description	dentin matrix acidic phosphoprotein 1
Other Description	AG1\|DMP-1\|dentin matrix protein 1
Swissprots	P98193
Accessions	EDL99499 P98193 BC129082 AAI29083 L11354 AAS55638 XM_006250622 XP_006250684 XM_008769994 XP_008768216 XM_008769995 XP_008768217 NM_203493 NP_987089
Function	May have a dual function during osteoblast differentiation. In the nucleus of undifferentiated osteoblasts, unphosphorylated form acts as a transcriptional component for activation of osteoblast-specific genes like osteocalcin. During the osteoblast to osteocyte transition phase it is phosphorylated and exported into the extracellular matrix, where it regulates nucleation of hydroxyapatite (By similarity). {ECO:0000250}.
Subcellular Location	Nucleus {ECO:0000250}. Cytoplasm {ECO:0000250}. Secreted, extracellular space, extracellular matrix {ECO:0000250}. Note=In proliferating preosteoblasts it is nuclear, during early maturation stage is cytoplasmic and in mature osteoblast localizes in the mineralized matrix. Export from the nucleus of differentiating osteoblast is triggered by the release of calcium from intracellular stores followed by a massive influx of this pool of calcium into the nucleus (By similarity). {ECO:0000250}.
Tissue Specificity	Expressed in tooth particularly in odontoblast and ameloblast.

Category	Protein
Source	Yeast or E.coli or Baculovirus or Mammalian cell
Species	Rat

Category	Protein
Prices	$1,255.00, $1,255.00, $1,475.00, $1,475.00, $2,050.00, $2,050.00, $2,515.00, $2,515.00
Sizes	500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell)
Source	E Coli or Yeast or Baculovirus or Mammalian Cell
Species	Rat

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