Gene Symbol | SH3BP1 |
---|---|
Entrez Gene | 23616 |
Alt Symbol | ARHGAP43 |
Species | Human |
Gene Type | protein-coding |
Description | SH3-domain binding protein 1 |
Other Description | 3BP-1|SH3 domain binding protein 1|SH3 domain-binding protein 1 |
Swissprots | Q9NSQ9 Q6ZVL9 Q5R3N0 Q96HQ5 Q6IBZ2 Q9Y3L3 |
Accessions | EAW60171 EAW60172 EAW60173 EAW60174 Q9Y3L3 AK124370 BAC85842 AK126556 BAC86592 AK301163 BAH13419 AL157480 CAB75671 AW452539 AY364241 AAQ76800 BC008282 AAH08282 CR456576 CAG30462 CU013175 CAK54606 CU013463 CAK54905 DQ892658 ABM83584 DQ895898 ABM86824 NM_018957 NP_061830 |
Function | Binds differentially to the SH3 domains of certain proteins of signal transduction pathways. This protein binds preferentially to the ABL1 proto-oncogene, SRC and GRB2. Shows GAP activity for Rac-related proteins but not for Rho- or Ras-related proteins. It inhibits PDGF-induced membrane ruffling mediated by Rac (By similarity). {ECO:0000250}. |
3BP1 CRISPR/Cas9 KO Plasmid (h) - sc-407775 from Santa Cruz Biotechnology
|
||||||||
3BP1 HDR Plasmid (h) - sc-407775-HDR from Santa Cruz Biotechnology
|
||||||||
3BP1 Double Nickase Plasmid (h) - sc-407775-NIC from Santa Cruz Biotechnology
|
||||||||
3BP1 Double Nickase Plasmid (h2) - sc-407775-NIC-2 from Santa Cruz Biotechnology
|
||||||||
3BP1 CRISPR Activation Plasmid (h) - sc-407775-ACT from Santa Cruz Biotechnology
|
||||||||
3BP1 CRISPR Activation Plasmid (h2) - sc-407775-ACT-2 from Santa Cruz Biotechnology
|
||||||||
3BP1 Lentiviral Activation Particles (h) - sc-407775-LAC from Santa Cruz Biotechnology
|
||||||||
3BP1 Lentiviral Activation Particles (h2) - sc-407775-LAC-2 from Santa Cruz Biotechnology
|
||||||||
3BP1 siRNA (h) - sc-77021 from Santa Cruz Biotechnology
|
||||||||
3BP1 shRNA Plasmid (h) - sc-77021-SH from Santa Cruz Biotechnology
|
||||||||
3BP1 shRNA (h) Lentiviral Particles - sc-77021-V from Santa Cruz Biotechnology
|
||||||||
MISSION® esiRNA - EHU091781 from Sigma-Aldrich
|
||||||||
CompoZr® Knockout ZFN Kit - CKOZFN19261 from Sigma-Aldrich
|
||||||||
CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND19261 from Sigma-Aldrich
|
||||||||
SH3BP1 siRNA (Human) - CRH8398 from Cohesion Biosciences
|
||||||||
SH3BP1 - MBS8222047 from MyBioSource
|
||||||||
shRNA set against Human SH3BP1 (NM_018957.3) - SHH406652 from Creative biogene
|
||||||||
shRNA set against Human SH3BP1(NM_018957.3) - SHR222646 from Creative biogene
|
||||||||
SH3BP1 shRNA Plasmid (Human) - CHH8398 from Cohesion Biosciences
|
||||||||
SH3BP1 miRNA 3'UTR clone - MiUTR1H-09361 from Creative biogene
|