TRPM3

Gene Symbol	TRPM3
Entrez Gene	80036
Alt Symbol	GON-2, LTRPC3, MLSN2
Species	Human
Gene Type	protein-coding
Description	transient receptor potential cation channel, subfamily M, member 3
Other Description	LTrpC-3\|long transient receptor potential channel 3\|melastatin 2\|melastatin-2\|transient receptor potential cation channel subfamily M member 3
Swissprots	A2A3F6 Q86Z00 Q86UL0 Q9H0X2 Q86WK3 Q86YZ9 Q86WK2 Q86Z01 Q9HCF6 Q86WK4 A9Z1Y7 Q86SH0 Q86SH6 Q5W5T7 Q86WK1 Q5VW03 Q5VW04 Q5VW02
Accessions	EAW62505 EAW62506 EAW62507 EAW62508 EAW62509 EAW62510 EAW62511 Q9HCF6 AB046836 BAB13442 AB099661 BAC55102 AB099662 BAC55103 AB099663 BAC55104 AB099664 BAC55105 AB099665 BAC55106 AF325212 AAG42856 AF536748 AAO49153 AF536749 AAO49154 AF536750 AAO49155 AF536751 AAO49156 AF536752 AAO49157 AF536753 AAO49158 AJ505025 CAD43604 AJ505026 CAD43605 AK021788 BAB13895 AK225732 AK308682 AL136545 CAB66480 BC022454 AAH22454 BC067733 AAH67733 BC094699 AAH94699 BC121821 AAI21822 BC134414 AAI34415 BC142972 AAI42973 BC172350 AAI72350 BM668925 CD104154 CD673832 KF987075 AHI18585 XM_011519035 XP_011517337 XM_011519036 XP_011517338 XM_011519037 XP_011517339 XM_011519038 XP_011517340 XM_011519039 XP_011517341 XM_011519040 XP_011517342 XM_011519041 XP_011517343 XM_011519042 XP_011517344 XM_011519043 XP_011517345 XM_011519044 XP_011517346 XM_011519045 XP_011517347 XM_011519046 XP_011517348 XM_011519047 XP_011517349 NM_001007470 NP_001007471 NM_001007471 NP_001007472 NM_020952 NP_066003 NM_024971 NP_079247 NM_206944 NP_996827 NM_206945 NP_996828 NM_206946 NP_996829 NM_206947 NP_996830 NM_206948 NP_996831
Function	Calcium channel mediating constitutive calcium ion entry. Its activity is increased by reduction in extracellular osmolarity, by store depletion and muscarinic receptor activation. {ECO:0000269\|PubMed:12672799, ECO:0000269\|PubMed:12672827}.
Subcellular Location	Membrane {ECO:0000269\|PubMed:12672827}; Multi-pass membrane protein {ECO:0000269\|PubMed:12672827}.
Tissue Specificity	Expressed primarily in the kidney and, at lower levels, in brain, testis, ovary, pancreas and spinal cord. Expression in the brain and kidney was determined at protein level. In the kidney, expressed predominantly in the collecting tubular epithelium in the medulla, medullary rays, and periglomerular regions; in the brain, highest levels are found in the cerebellum, choroid plexus, the locus coeruleus, the posterior thalamus and the substantia nigra. Down-regulated in renal tumors compared to normal kidney. {ECO:0000269\|PubMed:12672799, ECO:0000269\|PubMed:12672827}.

TRPM3 (H-300) - sc-98553 from Santa Cruz Biotechnology

Prices	$279.00
Sizes	200 µg/ml
Host	Rabbit
Clonality	Polyclonal

TRPM3 (H-300): sc-98553. Immunoperoxidase staining of formalin fixed, paraffin-embedded human kidney tissue showing cytoplasmic staining of cells in tubules.

TRPM3 (K-17) - sc-79165 from Santa Cruz Biotechnology

Prices	$279.00
Sizes	200 µg/ml
Host	Goat
Clonality	Polyclonal

TRPM3 (V-18) - sc-79167 from Santa Cruz Biotechnology

Prices	$279.00
Sizes	200 µg/ml
Host	Goat
Clonality	Polyclonal

TRPM3 (V-18): sc-79167. Western blot analysis of TRPM3 expression in U-251-MG whole cell lysate.

Anti-TRPM3 antibody - ab74848 from Abcam

Host	Rabbit
Clonality	Polyclonal

ab74848 stained A498 cells. The cells were 4% formaldhyde fixed for 10 minutes at XXX* and then incubated in 1%BSA / 10% normal goat serum / 0.3M glycine in 0.1% PBS-Tween for 1hour at room temperature to permeabilise the cells and block non-specific protein-protein interactions. The cells were then incubated with the antibody (ab74848 at 1/200 dilution) overnight at +4°C. The secondary antibody (pseudo-colored green) was Goat Anti-Rabbit IgG H&L (Alexa Fluor® 488) preadsorbed (ab150081) used at a 1/1000 dilution for 1hour at room temperature. Alexa Fluor® 594 WGA was used to label plasma membranes (pseudo-colored red) at a 1/200 dilution for 1hour at room temperature. DAPI was used to stain the cell nuclei (pseudo-colored blue) at a concentration of 1.43µM for 1hour at room temperature.

Anti-TRPM3 antibody - ab63016 from Abcam

Host	Rabbit
Clonality	Polyclonal

Anti-TRPM3 antibody - ab63081 from Abcam

Host	Sheep
Clonality	Polyclonal

Anti-TRPM3 Antibody (N-Terminus) - LS-C95016 from LifeSpan Bioscience

Prices	$325.00
Sizes	500 µg
Host	Rabbit
Clonality	Polyclonal

Anti-TRPM3 Antibody (Internal) - LS-C153581 from LifeSpan Bioscience

Prices	$345.00
Sizes	100 µg
Host	Rabbit
Clonality	Polyclonal

Anti-TRPM3 Antibody (Internal) - LS-C145085 from LifeSpan Bioscience

Prices	$365.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

Anti-TRPM3 Antibody (aa666-715) - LS-C31799 from LifeSpan Bioscience

Prices	$325.00
Sizes	100 µg
Host	Rabbit
Clonality	Polyclonal

Anti-TRPM3 Antibody (aa201-250) - LS-C30775 from LifeSpan Bioscience

Prices	$325.00
Sizes	100 µg
Host	Rabbit
Clonality	Polyclonal

Anti-TRPM3 Antibody (aa197-246) - LS-C30771 from LifeSpan Bioscience

Prices	$325.00
Sizes	100 µg
Host	Rabbit
Clonality	Polyclonal

Anti-TRPM3 Antibody (aa198-247) - LS-C205676 from LifeSpan Bioscience

Prices	$365.00
Sizes	50 µg
Host	Rabbit
Clonality	Polyclonal

TRPM3 antibody Western Blot of Stomach Tumor. Antibody dilution: 1 ug/ml.

Anti-TRPM3 Antibody (aa51-81) - LS-C160233 from LifeSpan Bioscience

Prices	$250.00
Sizes	50 µg
Host	Rabbit
Clonality	Polyclonal

Western blot analysis of TRPM3 Antibody (N-term) in MDA-MB435 cell line lysates (35 ug/lane). TRPM3 (arrow) was detected using the purified Pab.

TRPM3 Antibody - NBP1-80210 from Novus Biologicals

Prices	$139.00, $299.00
Sizes	20 µl, 100 µl
Host	Rabbit
Clonality	Polyclonal

Western Blot: TRPM3 Antibody [NBP1-80210] - Jurkat cell lysate, concentration 2.5 ug/ml.

TRPM3 Antibody - NB100-98864 from Novus Biologicals

Prices	$299.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

TRPM3 Antibody - NBP1-46344 from Novus Biologicals

Prices	$329.00
Sizes	100 µl
Host	Goat
Clonality	Polyclonal

TRPM3 Antibody - NB110-75004 from Novus Biologicals

Prices	$329.00
Sizes	100 µl
Host	Sheep
Clonality	Polyclonal

TRPM3 Polyclonal Antibody - bs-9046R from Bioss

Prices	$269.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

Anti-TRPM3 antibody produced in rabbit - SAB2106400 from Sigma-Aldrich

Prices	$341.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

<B>Immunoblotting</B><BR/>Anti-TRPM3: <B>Cat. No. SAB2106400</B>: Western blot analysis of TRPM3 with TRPM3 (transient receptor potential cation channel, subfamily M, member 3) antibody against the N terminal of TRPM3) 100 μg) antibody at 1.25 μg/mL.

Anti-TRPM3 (AB3) antibody produced in rabbit - AV35609 from Sigma-Aldrich

Prices	$267.50, $267.50
Sizes	100 µg, 100 µl
Host	Rabbit
Clonality	Polyclonal

<B>Immunoblotting</B><BR/>Cell Type: HepG2 (<B>Cat. No. AV35609</B>).<BR/><B>Lanes</B><BR/>1. Antibody dilution (concentration) 1.25 μg/mL in cell type HepG2

Anti-TRPM3 antibody produced in rabbit - SAB2106401 from Sigma-Aldrich

Prices	$341.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

<B>Immunoblotting</B><BR/>Anti-TRPM3: <B>Cat. No. SAB2106401</B>: Western blot analysis of TRPM3 with TRPM3 (transient receptor potential cation channel, subfamily M, member 3) antibody against the N terminal of TRPM3) (50 μg) antibody at 2 μg/mL.

TRPM1 Antibody - C-terminal region (ARP35608_P050) - ARP35608_P050 from Aviva Systems Biology

Prices	$289.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

TRPM3 antibody - N-terminal region (ARP35609_T100) - ARP35609_T100 from Aviva Systems Biology

Prices	$229.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

TRPM3 antibody - N-terminal region (ARP36768_T100) - ARP36768_T100 from Aviva Systems Biology

Prices	$229.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

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