Gene Symbol | DDX4 |
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Entrez Gene | 54514 |
Alt Symbol | VASA |
Species | Human |
Gene Type | protein-coding |
Description | DEAD (Asp-Glu-Ala-Asp) box polypeptide 4 |
Other Description | DEAD box protein 4|DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 4|probable ATP-dependent RNA helicase DDX4|vasa homolog |
Swissprots | A8K8Q2 D6RDK4 Q9NYB1 Q5M7Z3 Q9NQI0 E9PCD8 Q86VX0 B3KSF4 Q9NT92 |
Accessions | CBH19257 EAW54929 Q9NQI0 AF262962 AAF72705 AK093439 BAG52716 AK292417 BAF85106 AK308300 AL137462 CAB70750 AY004154 AAF86585 BC030638 BC047455 AAH47455 BC088362 AAH88362 BI559479 DB022413 DB051674 DB457419 DB508256 XM_005248545 XP_005248602 XM_005248547 XP_005248604 XM_011543495 XP_011541797 XM_011543496 XP_011541798 XM_011543497 XP_011541799 NM_019039 NM_001142549 NP_001136021 NM_001166533 NP_001160005 NM_001166534 NP_001160006 NM_024415 NP_077726 |
Function | May play a role in germ cell development. May play a role in sperm motility. {ECO:0000269|PubMed:10920202, ECO:0000269|PubMed:21034600}. |
Subcellular Location | Cytoplasm {ECO:0000269|PubMed:10920202, ECO:0000269|PubMed:21421998}. Cytoplasm, perinuclear region {ECO:0000250}. |
Tissue Specificity | Expressed only in ovary and testis. Expressed in migratory primordial germ cells in the region of the gonadal ridge in both sexes. {ECO:0000269|PubMed:10920202}. |
VASA CRISPR/Cas9 KO Plasmid (h) - sc-402228 from Santa Cruz Biotechnology
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VASA HDR Plasmid (h) - sc-402228-HDR from Santa Cruz Biotechnology
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VASA Double Nickase Plasmid (h) - sc-402228-NIC from Santa Cruz Biotechnology
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VASA Double Nickase Plasmid (h2) - sc-402228-NIC-2 from Santa Cruz Biotechnology
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VASA CRISPR Activation Plasmid (h) - sc-402228-ACT from Santa Cruz Biotechnology
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VASA CRISPR Activation Plasmid (h2) - sc-402228-ACT-2 from Santa Cruz Biotechnology
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VASA Lentiviral Activation Particles (h) - sc-402228-LAC from Santa Cruz Biotechnology
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VASA Lentiviral Activation Particles (h2) - sc-402228-LAC-2 from Santa Cruz Biotechnology
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VASA siRNA (h) - sc-61772 from Santa Cruz Biotechnology
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VASA shRNA Plasmid (h) - sc-61772-SH from Santa Cruz Biotechnology
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VASA shRNA (h) Lentiviral Particles - sc-61772-V from Santa Cruz Biotechnology
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VASA RNAi - H00054514-R03 from Novus Biologicals
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VASA RNAi - H00054514-R04 from Novus Biologicals
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MISSION® esiRNA - EHU097691 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN7056 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND7056 from Sigma-Aldrich
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DDX4 siRNA (Human) - CRJ0107 from Cohesion Biosciences
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DDX4 - MBS8232847 from MyBioSource
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Human DDX4 siRNA - orb270608 from Biorbyt
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DDX4 shRNA Plasmid (Human) - CHJ0107 from Cohesion Biosciences
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DDX4 miRNA 3'UTR clone - MiUTR4H-TG02621 from Creative biogene
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