SLC26A5

Gene Symbol	SLC26A5
Entrez Gene	375611
Alt Symbol	DFNB61, PRES
Species	Human
Gene Type	protein-coding
Description	solute carrier family 26 (anion exchanger), member 5
Other Description	prestin|prestin (motor protein)
Swissprots	Q7Z7F3 Q86UG0 Q86UF9 P58743 Q496J2 Q86UF8
Accessions	EAW83334 EAW83335 P58743 AF523354 AAP31417 AK126898 AY256823 AAP31532 AY256824 AAP31533 AY256825 AAP31534 AY289133 AAP43685 AY289134 AAP43686 BC100832 AAI00833 BC100833 AAI00834 BC100834 AAI00835 BC100835 AAI00836 DA197655 XM_011516170 XP_011514472 NM_001167962 NP_001161434 NM_198999 NP_945350 NM_206883 NP_996766 NM_206884 NP_996767 NM_206885 NP_996768 NR_120441 NR_120442 NR_120443
Function	Motor protein that converts auditory stimuli to length changes in outer hair cells and mediates sound amplification in the mammalian hearing organ. Prestin is a bidirectional voltage- to-force converter, it can operate at microsecond rates. It uses cytoplasmic anions as extrinsic voltage sensors, probably chloride and bicarbonate. After binding to a site with millimolar affinity, these anions are translocated across the membrane in response to changes in the transmembrane voltage. They move towards the extracellular surface following hyperpolarization, and towards the cytoplasmic side in response to depolarization. As a consequence, this translocation triggers conformational changes in the protein that ultimately alter its surface area in the plane of the plasma membrane. The area decreases when the anion is near the cytoplasmic face of the membrane (short state), and increases when the ion has crossed the membrane to the outer surface (long state). So, it acts as an incomplete transpo
Subcellular Location	Cell membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}. Note=Lateral wall of outer hair cells. {ECO:0000250}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human SLC26A5 full length protein - ab166381 from Abcam Category Protein Source Wheat germ Species Human

SLC26A5 Antibody Blocking Peptide - LS-E16233 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

SLC26A5 Antibody Blocking Peptide - LS-E26966 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human SLC26A5 Protein - H00375611-P01 from Novus Biologicals Category Protein Prices $319.00 Sizes 2 µg Source Wheat Germ Species Human

SLC26A5/prestin blocking peptide - GTX88472-PEP from GeneTex Category Peptide Prices $239.00 Sizes 100 μg Species Human

SLC26A5 Blocking Peptide - 33R-3083 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

SLC26A5 Peptide - AC21-1795-P from Abcore Category Peptide Prices $160.00 Sizes 100 µg

SLC26A5 / Prestin - H00375611-P01 from Acris Antibodies Category Protein Prices $310.00 Sizes 2 µg Species Human

Prestin Peptide - 46-931P from ProSci Category Peptide

SLC26A5 fusion protein - ag16631 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

Recombinant Human SLC26A5, GST-tagged - SLC26A5-112H from Creative Biomart Category Protein Source Wheat germ Species Human

Prestin, Recombinant Protein - MBS956246 from MyBioSource Category Protein Prices $190.00, $305.00, $460.00, $580.00, $750.00, $950.00, $950.00, $1,170.00, $1,180.00, $1,400.00, $1,400.00, $1,860.00, $1,860.00, $2,760.00 Sizes 50 µg (Yeast), 50 µg (E-Coli), 200 µg (Yeast), 200 µg (E-Coli), 500 µg (Yeast), 50 µg (Baculovirus), 500 µg (E-Coli), 50 µg (Mammalian-Cell), 1 mg (Yeast), 1 mg (E-Coli), 100 µg (Baculovirus), 100 µg (Mammalian-Cell), 500 µg (Baculovirus), 1 mg (Baculovirus) Source E Coli or Yeast or Baculovirus or Mammalian Cell

SLC26A5/prestin, Peptide - MBS426514 from MyBioSource Category Peptide Prices $175.00 Sizes 100 µg Species Human

SLC26A5 Peptide, Human - M34GP14460H from Creative Peptides Category Peptide Source Synthetic. Species Human

SLC26A5 Recombinant Protein (OPCA02794) - OPCA02794 from Aviva Systems Biology Category Protein Prices $250.00 Sizes 50 µg Source Human

Human SLC26A5 protein - orb358258 from Biorbyt Category Protein Prices $221.00, $366.00, $646.00, $1,071.00, $1,692.00 Sizes 10 μg, 50 μg, 200 μg, 500 μg, 1 mg Species Human

Recombinant Homo sapiens Prestin - AP72784 from Signalway Antibody Category Protein Prices $260.00, $735.00, $1,240.00, $1,975.00 Sizes 50 µg, 200 µg, 500 µg, 1 mg Source Yeast

Prestin, Recombinant Protein - MBS9422497 from MyBioSource Category Protein Prices $280.00, $665.00, $1,080.00, $1,690.00 Sizes 50 µg, 200 µg, 500 µg, 1 mg Source Yeast Species Human

Recombinant Human SLC26A5 Protein, His-tagged - SLC26A5-1520H from Creative Biomart Category Protein Source Yeast Species Human

Search more