Gene Symbol | SH3GL1 |
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Entrez Gene | 6455 |
Alt Symbol | CNSA1, EEN, SH3D2B, SH3P8 |
Species | Human |
Gene Type | protein-coding |
Description | SH3-domain GRB2-like 1 |
Other Description | EEN fusion partner of MLL|SH3 domain protein 2B|SH3 domain-containing GRB2-like protein 1|SH3-containing Grb-2-like 1 protein|endophilin-2|endophilin-A2|extra 11-19 leukemia fusion|extra eleven-nineteen leukemia fusion gene protein |
Swissprots | E7EVZ4 B4DRA1 Q99961 Q99668 M0QZV5 |
Accessions | AAD24591 AAF04290 EAW69227 EAW69228 EAW69229 Q99961 AK097616 AK299166 BAG61213 AK315450 BAG37838 AY364240 AAQ76799 BC000089 AAH00089 BC001094 AAH01094 BC001270 AAH01270 BC014387 AAH14387 BC073825 BC098565 AAH98565 BU838380 CK820395 CR542087 CAG46884 DQ891258 ABM82184 DQ894444 ABM85370 U65999 AAB86800 X99656 CAA67970 XM_011528183 XP_011526485 NM_001199943 NP_001186872 NM_001199944 NP_001186873 NM_003025 NP_003016 |
Function | Implicated in endocytosis. May recruit other proteins to membranes with high curvature (By similarity). {ECO:0000250}. |
Subcellular Location | Cytoplasm {ECO:0000250}. Early endosome membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}. Cell projection, podosome {ECO:0000269|PubMed:23285027}. Note=Associated with postsynaptic endosomes in hippocampal neurons. {ECO:0000250}. |
Tissue Specificity | Ubiquitous. Higher expression in pancreas, placenta, prostate, testis and uterus. |
Top Pathways | Endocytosis |
Human SH3 containing Grb 2 like 1 protein full length protein - ab132997 from Abcam
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Human SH3 containing Grb 2 like 1 protein full length protein - ab132998 from Abcam
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SH3GL1 / EEN Antibody Blocking Peptide - LS-E4714 from LifeSpan Bioscience
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SH3GL1 / EEN Antibody Blocking Peptide - LS-E27597 from LifeSpan Bioscience
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SH3GL1 / EEN Antibody Blocking Peptide - LS-E20548 from LifeSpan Bioscience
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Recombinant Human EEN Protein - H00006455-P01 from Novus Biologicals
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Recombinant Human EEN Protein - H00006455-P02 from Novus Biologicals
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EEN Partial Recombinant Protein - H00006455-Q01 from Novus Biologicals
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SH3GL1-Antibody-C-term-Blocking-Peptide - BP17084b from Abgent, a WuXi AppTec company
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SH3GL1 Blocking Peptide - 33R-5248 from Fitzgerald
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SH3 Containing Grb like 1 Protein Peptide - AC21-2417-P from Abcore
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Endophilin-A2 - H00006455-P01-10 from Acris Antibodies
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Endophilin-A2 - H00006455-P01-25 from Acris Antibodies
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Endophilin-A2 - H00006455-P02 from Acris Antibodies
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Endophilin-A2 - H00006455-P02-10 from Acris Antibodies
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Endophilin-A2 - H00006455-P02-25 from Acris Antibodies
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Endophilin-A2 - H00006455-Q01-10 from Acris Antibodies
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Endophilin-A2 - H00006455-Q01-25 from Acris Antibodies
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SH3GL1 Peptide - 42-410P from ProSci
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Recombinant Human SH3GL1, His-tagged - SH3GL1-30812TH from Creative Biomart
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Recombinant Human Endophilin-A2(SH3GL1) - CSB-YP859949HU CSB-EP859949HU CSB-BP859949HU CSB-MP859949HU from Cusabio
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SH3GL1 Protein - abx164360 from Abbexa
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Endophilin-A2 - TP301552 from Acris Antibodies
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Endophilin-A2, Peptide - MBS427705 from MyBioSource
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EEN Recombinant Protein Antigen - NBP1-85522PEP from Novus Biologicals
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