FOXN4

Gene Symbol FOXN4
Entrez Gene 121643
Alt Symbol -
Species Human
Gene Type protein-coding
Description forkhead box N4
Other Description forkhead box protein N4|forkhead/winged helix transcription factor FOXN4
Swissprots Q96NZ1 Q96NZ0 Q6ZMR4
Accessions EAW97856 EAW97857 Q96NZ1 AA421288 AF425596 AAL23949 AF425597 AAL23950 AK093286 AK131519 BAD18661 BC113073 AAI13074 BC146825 AAI46826 XM_011537919 XP_011536221 XM_011537920 XP_011536222 XM_011537921 XP_011536223 XM_011537922 XP_011536224 XM_011537923 XP_011536225 NM_213596 NP_998761
Function Transcription factor essential for neural and some non- neural tissues development, such as retina and lung respectively. Binds to an 11-bp consensus sequence containing the invariant tetranucleotide 5'-ACGC-3'. During development of the central nervous system, is required to specify the amacrine and horizontal cell fates from multipotent retinal progenitors while suppressing the alternative photoreceptor cell fates through activating DLL4- NOTCH signaling. Also acts synergistically with ASCL1/MASH1 to activate DLL4-NOTCH signaling and drive commitment of p2 progenitors to the V2b interneuron fates during spinal cord neurogenesis. In development of non-neural tissues, plays an essential role in the specification of the atrioventricular canal and is indirectly required for patterning the distal airway during lung development (By similarity). {ECO:0000250}.
Subcellular Location Nucleus {ECO:0000255|PROSITE- ProRule:PRU00089}.

FOXN4 CRISPR/Cas9 KO Plasmid (h) - sc-410512 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

FOXN4 HDR Plasmid (h) - sc-410512-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

FOXN4 Double Nickase Plasmid (h) - sc-410512-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

FOXN4 Double Nickase Plasmid (h2) - sc-410512-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

FOXN4 CRISPR Activation Plasmid (h) - sc-410512-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

FOXN4 CRISPR Activation Plasmid (h2) - sc-410512-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

FOXN4 Lentiviral Activation Particles (h) - sc-410512-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

FOXN4 Lentiviral Activation Particles (h2) - sc-410512-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

FOXN4 siRNA (h) - sc-62343 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

FOXN4 shRNA Plasmid (h) - sc-62343-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

FOXN4 shRNA (h) Lentiviral Particles - sc-62343-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

FOXN4 RNAi - H00121643-R01 from Novus Biologicals

Category siRNA
Prices $409.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU151911 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN8910 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND8910 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR09929 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr09929

FOXN4 siRNA (Human) - CRJ4684 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

FOXN4 - MBS8206323 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human FOXN4 (NM_213596.2) - SHH296741 from Creative biogene

Category siRNA
Species Reactivities Human

shRNA set against Human FOXN4(NM_213596.2) - SHH066935 from Creative biogene

Category siRNA
Species Reactivities Human

FOXN4 shRNA Plasmid (Human) - CHJ4684 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

FOXN4 miRNA 3'UTR clone - MiUTR1H-03830 from Creative biogene

Species Reactivities Human
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