| Gene Symbol |
SPTSSA
|
| Entrez Gene |
171546
|
| Alt Symbol |
C14orf147, SSSPTA
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
serine palmitoyltransferase, small subunit A
|
| Other Description |
serine palmitoyltransferase small subunit A|small subunit of serine palmitoyltransferase A
|
| Swissprots |
Q8WTZ7 B2RD54 Q969W0 D3DS93
|
| Accessions |
EAW65923 EAW65924 Q969W0 AI765163 AK001993 AK315409 BAG37801 AL080066 BC016805 AAH16805 BC016808 AAH16808 BC021701 AAH21701 BC068480 AAH68480 HQ447916 ADQ32400 NM_138288 NP_612145
|
| Function |
Stimulates the activity of serine palmitoyltransferase (SPT). The composition of the serine palmitoyltransferase (SPT) complex determines the substrate preference. The SPTLC1-SPTLC2- SPTSSA complex shows a strong preference for C16-CoA substrate, while the SPTLC1-SPTLC3-SPTSSA isozyme uses both C14-CoA and C16- CoA as substrates, with a slight preference for C14-CoA. {ECO:0000269|PubMed:19416851}.
|
| Subcellular Location |
Endoplasmic reticulum membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
|