| Gene Symbol |
DHTKD1
|
| Entrez Gene |
55526
|
| Alt Symbol |
AMOXAD, CMT2Q
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
dehydrogenase E1 and transketolase domain containing 1
|
| Other Description |
dehydrogenase E1 and transketolase domain-containing protein 1|probable 2-oxoglutarate dehydrogenase E1 component DHKTD1, mitochondrial
|
| Swissprots |
Q9HCE2 Q96HY7 Q9BUM8 Q68CU5
|
| Accessions |
EAW86327 Q96HY7 AA009773 AA393480 AI823832 AK309810 AL359587 AW083293 BC002477 AAH02477 BC007955 AAH07955 BG469693 BI333272 BQ420710 BU187564 BU855972 BU927608 CB134342 CF593518 CR749726 CAH18489 HY039281 R72130 NM_018706 NP_061176
|
| Function |
The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components: 2- oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3) (By similarity). {ECO:0000250}.
|
| Subcellular Location |
Mitochondrion {ECO:0000269|PubMed:23141294}.
|