Gene Symbol | DHTKD1 |
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Entrez Gene | 55526 |
Alt Symbol | AMOXAD, CMT2Q |
Species | Human |
Gene Type | protein-coding |
Description | dehydrogenase E1 and transketolase domain containing 1 |
Other Description | dehydrogenase E1 and transketolase domain-containing protein 1|probable 2-oxoglutarate dehydrogenase E1 component DHKTD1, mitochondrial |
Swissprots | Q9HCE2 Q96HY7 Q9BUM8 Q68CU5 |
Accessions | EAW86327 Q96HY7 AA009773 AA393480 AI823832 AK309810 AL359587 AW083293 BC002477 AAH02477 BC007955 AAH07955 BG469693 BI333272 BQ420710 BU187564 BU855972 BU927608 CB134342 CF593518 CR749726 CAH18489 HY039281 R72130 NM_018706 NP_061176 |
Function | The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components: 2- oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3) (By similarity). {ECO:0000250}. |
Subcellular Location | Mitochondrion {ECO:0000269|PubMed:23141294}. |
DHTKD1 CRISPR/Cas9 KO Plasmid (h) - sc-407613 from Santa Cruz Biotechnology
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DHTKD1 HDR Plasmid (h) - sc-407613-HDR from Santa Cruz Biotechnology
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DHTKD1 Double Nickase Plasmid (h) - sc-407613-NIC from Santa Cruz Biotechnology
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DHTKD1 Double Nickase Plasmid (h2) - sc-407613-NIC-2 from Santa Cruz Biotechnology
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DHTKD1 CRISPR Activation Plasmid (h) - sc-407613-ACT from Santa Cruz Biotechnology
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DHTKD1 CRISPR Activation Plasmid (h2) - sc-407613-ACT-2 from Santa Cruz Biotechnology
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DHTKD1 Lentiviral Activation Particles (h) - sc-407613-LAC from Santa Cruz Biotechnology
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DHTKD1 Lentiviral Activation Particles (h2) - sc-407613-LAC-2 from Santa Cruz Biotechnology
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DHTKD1 siRNA (h) - sc-90728 from Santa Cruz Biotechnology
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DHTKD1 shRNA Plasmid (h) - sc-90728-SH from Santa Cruz Biotechnology
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DHTKD1 shRNA (h) Lentiviral Particles - sc-90728-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU152501 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN7211 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND7211 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR11309 from Sigma-Aldrich
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DHTKD1 siRNA (Human) - CRJ0725 from Cohesion Biosciences
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DHTKD1 - MBS8233438 from MyBioSource
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shRNA set against Human DHTKD1(NM_018706.5) - SHH004385 from Creative biogene
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Human DHTKD1 siRNA - orb271226 from Biorbyt
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DHTKD1 shRNA Plasmid (Human) - CHJ0725 from Cohesion Biosciences
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DHTKD1 miRNA 3'UTR clone - MiUTR1H-02814 from Creative biogene
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