| Gene Symbol | DDOST |
|---|---|
| Entrez Gene | 1650 |
| Alt Symbol | AGER1, CDG1R, OKSWcl45, OST, OST48, WBP1 |
| Species | Human |
| Gene Type | protein-coding |
| Description | dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit (non-catalytic) |
| Other Description | advanced glycation endproduct receptor 1|dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit|dolichyl-diphosphooligosaccharide-protein glycotransferase|oligosaccharyl transferase 48 kDa subunit|oligosaccharyltransferase 48 kDa subunit|oligosaccharyltransferase subunit 48 |
| Swissprots | B4DLI2 B4DJE3 Q9BUI2 O43244 Q8NI93 B2RDQ4 P39656 Q5VWA5 |
| Accessions | BAA23670 BAB82435 EAW94936 EAW94937 EAW94938 EAW94939 EAW94940 P39656 AB062391 BAB93478 AK296041 BAG58805 AK297009 BAG59544 AK315633 BAG38001 BC002594 AAH02594 BP233191 CB137813 CB988524 D29643 BAA06126 DQ891927 ABM82853 DQ895114 ABM86040 NM_005216 NP_005207 |
| Function | Essential subunit of the N-oligosaccharyl transferase (OST) complex which catalyzes the transfer of a high mannose oligosaccharide from a lipid-linked oligosaccharide donor to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains. |
| Subcellular Location | Endoplasmic reticulum membrane; Single-pass type I membrane protein. |
| Top Pathways | N-Glycan biosynthesis, Protein processing in endoplasmic reticulum |