Gene Symbol | DDOST |
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Entrez Gene | 1650 |
Alt Symbol | AGER1, CDG1R, OKSWcl45, OST, OST48, WBP1 |
Species | Human |
Gene Type | protein-coding |
Description | dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit (non-catalytic) |
Other Description | advanced glycation endproduct receptor 1|dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit|dolichyl-diphosphooligosaccharide-protein glycotransferase|oligosaccharyl transferase 48 kDa subunit|oligosaccharyltransferase 48 kDa subunit|oligosaccharyltransferase subunit 48 |
Swissprots | B4DLI2 B4DJE3 Q9BUI2 O43244 Q8NI93 B2RDQ4 P39656 Q5VWA5 |
Accessions | BAA23670 BAB82435 EAW94936 EAW94937 EAW94938 EAW94939 EAW94940 P39656 AB062391 BAB93478 AK296041 BAG58805 AK297009 BAG59544 AK315633 BAG38001 BC002594 AAH02594 BP233191 CB137813 CB988524 D29643 BAA06126 DQ891927 ABM82853 DQ895114 ABM86040 NM_005216 NP_005207 |
Function | Essential subunit of the N-oligosaccharyl transferase (OST) complex which catalyzes the transfer of a high mannose oligosaccharide from a lipid-linked oligosaccharide donor to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains. |
Subcellular Location | Endoplasmic reticulum membrane; Single-pass type I membrane protein. |
Top Pathways | N-Glycan biosynthesis, Protein processing in endoplasmic reticulum |
OST48 CRISPR/Cas9 KO Plasmid (h) - sc-403323 from Santa Cruz Biotechnology
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OST48 HDR Plasmid (h) - sc-403323-HDR from Santa Cruz Biotechnology
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OST48 Double Nickase Plasmid (h) - sc-403323-NIC from Santa Cruz Biotechnology
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OST48 Double Nickase Plasmid (h2) - sc-403323-NIC-2 from Santa Cruz Biotechnology
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OST48 CRISPR Activation Plasmid (h) - sc-403323-ACT from Santa Cruz Biotechnology
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OST48 CRISPR Activation Plasmid (h2) - sc-403323-ACT-2 from Santa Cruz Biotechnology
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OST48 Lentiviral Activation Particles (h) - sc-403323-LAC from Santa Cruz Biotechnology
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OST48 Lentiviral Activation Particles (h2) - sc-403323-LAC-2 from Santa Cruz Biotechnology
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OST48 siRNA (h) - sc-40788 from Santa Cruz Biotechnology
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OST48 shRNA Plasmid (h) - sc-40788-SH from Santa Cruz Biotechnology
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OST48 shRNA (h) Lentiviral Particles - sc-40788-V from Santa Cruz Biotechnology
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DDOST RNAi - H00001650-R01 from Novus Biologicals
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MISSION® esiRNA - EHU028651 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN7030 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND7030 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR05118 from Sigma-Aldrich
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DDOST siRNA (Human) - CRH1163 from Cohesion Biosciences
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DDOST - MBS8224167 from MyBioSource
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shRNA set against Human DDOST (NM_005216.4) - SHH275713 from Creative biogene
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shRNA set against Human DDOST(NM_005216.4) - SHG226033 from Creative biogene
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Human DDOST siRNA - orb261665 from Biorbyt
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DDOST shRNA Plasmid (Human) - CHH1163 from Cohesion Biosciences
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DDOST miRNA 3'UTR clone - MiUTR1H-02714 from Creative biogene
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