| Gene Symbol |
Atg9a
|
| Entrez Gene |
245860
|
| Alt Symbol |
AU019532, Apg9l1, Atg9, Atg9l1
|
| Species |
Mouse
|
| Gene Type |
protein-coding
|
| Description |
autophagy related 9A
|
| Other Description |
APG9 autophagy 9-like 1|APG9-like 1|autophagy protein 9|autophagy-related 9-like 1|autophagy-related 9A|autophagy-related protein 9A
|
| Swissprots |
Q68FE2
|
| Accessions |
EDL00374 EDL00375 Q68FE2 AK043624 BAC31599 AK195501 AK203199 AK205404 AK210178 AM085510 CAJ30208 AU019532 BC034139 AAH34139 BC056488 BC079884 AAH79884 BC082307 BK004020 DAA05201 XM_011238687 XP_011236989 XM_011238688 XP_011236990 XM_011238689 XP_011236991 XM_011238690 XP_011236992 NM_001003917 NP_001003917 NM_001288612 NP_001275541 NM_001288613 NP_001275542 NR_109938
|
| Function |
Involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation. Plays a key role in the organization of the preautophagosomal structure/phagophore assembly site (PAS), the nucleating site for formation of the sequestering vesicle. Cycles between a juxta-nuclear trans-Golgi network compartment and late endosomes. Nutrient starvation induces accumulation on autophagosomes. Starvation-dependent trafficking requires ULK1, ATG13 and SUPT20H (By similarity). Required for carbonyl cyanide m-chlorophenylhydrazone (CCCP)-induced ATG8 family proteins lipidation, a key autophagy step. {ECO:0000250, ECO:0000269|PubMed:23402761}.
|
| Subcellular Location |
Cytoplasmic vesicle, autophagosome membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}. Golgi apparatus, trans-Golgi network membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}. Late endosome membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}.
|