| Gene Symbol |
SCN4A
|
| Entrez Gene |
6329
|
| Alt Symbol |
HOKPP2, HYKPP, HYPP, NAC1A, Na(V)1.4, Nav1.4, SkM1
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
sodium channel, voltage gated, type IV alpha subunit
|
| Other Description |
skeletal muscle voltage-dependent sodium channel type IV alpha subunit|sodium channel protein skeletal muscle subunit alpha|sodium channel protein type 4 subunit alpha|sodium channel protein type IV subunit alpha|sodium channel, voltage-gated, type IV, alpha subunit|voltage-gated sodium channel subunit alpha Nav1.4
|
| Swissprots |
Q15478 Q16447 Q7Z6B1 P35499
|
| Accessions |
AAA75557 AAB21450 AAB59624 AAC14673 AAG43105 EAW94225 EAW94226 P35499 AY212253 AAO83647 BC172375 AAI72375 HG509334 M81758 AAA60554 XM_005257566 XP_005257623 NM_000334 NP_000325
|
| Function |
This protein mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. This sodium channel may be present in both denervated and innervated skeletal muscle.
|
| Subcellular Location |
Membrane; Multi-pass membrane protein.
|