Gene Symbol |
ATP4B
|
Entrez Gene |
496
|
Alt Symbol |
ATP6B
|
Species |
Human
|
Gene Type |
protein-coding
|
Description |
ATPase, H+/K+ exchanging, beta polypeptide
|
Other Description |
ATPase, H+/K+ transporting, beta polypeptide|gastric H(+)/K(+) ATPase subunit beta|gastric H+/K+ ATPase beta subunit|gastric hydrogen-potassium ATPase, beta|potassium-transporting ATPase beta chain|potassium-transporting ATPase subunit beta|proton pump beta chain
|
Swissprots |
P51164 B1B0N8
|
Accessions |
BAA23425 EAX09220 EAX09221 P51164 AK310129 BC029059 AAH29059 BC042846 BI764514 BM782259 BM923761 BX100065 DA964061 DQ890817 ABM81743 DQ893973 ABM84899 M75110 AAA35987 NM_000705 NP_000696
|
Function |
Required for stabilization and maturation of the catalytic proton pump alpha subunit and may also involved in cell adhesion and establishing epithelial cell polarity. {ECO:0000269|PubMed:19694409}.
|
Subcellular Location |
Cell membrane; Single-pass type II membrane protein.
|
Top Pathways |
Collecting duct acid secretion, Gastric acid secretion, Oxidative phosphorylation
|