Gene Symbol | ATP4B |
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Entrez Gene | 496 |
Alt Symbol | ATP6B |
Species | Human |
Gene Type | protein-coding |
Description | ATPase, H+/K+ exchanging, beta polypeptide |
Other Description | ATPase, H+/K+ transporting, beta polypeptide|gastric H(+)/K(+) ATPase subunit beta|gastric H+/K+ ATPase beta subunit|gastric hydrogen-potassium ATPase, beta|potassium-transporting ATPase beta chain|potassium-transporting ATPase subunit beta|proton pump beta chain |
Swissprots | P51164 B1B0N8 |
Accessions | BAA23425 EAX09220 EAX09221 P51164 AK310129 BC029059 AAH29059 BC042846 BI764514 BM782259 BM923761 BX100065 DA964061 DQ890817 ABM81743 DQ893973 ABM84899 M75110 AAA35987 NM_000705 NP_000696 |
Function | Required for stabilization and maturation of the catalytic proton pump alpha subunit and may also involved in cell adhesion and establishing epithelial cell polarity. {ECO:0000269|PubMed:19694409}. |
Subcellular Location | Cell membrane; Single-pass type II membrane protein. |
Top Pathways | Collecting duct acid secretion, Gastric acid secretion, Oxidative phosphorylation |
H + /K + ATPase β siRNA (h) - sc-75217 from Santa Cruz Biotechnology
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H + /K + ATPase β shRNA Plasmid (h) - sc-75217-SH from Santa Cruz Biotechnology
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H + /K + ATPase β shRNA (h) Lentiviral Particles - sc-75217-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU046381 from Sigma-Aldrich
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MISSION® esiRNA - EHU074181 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN3693 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND3693 from Sigma-Aldrich
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ATP4B siRNA (Human) - CRH0349 from Cohesion Biosciences
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Hydrogen Potassium ATPase Beta RNAi - H00000496-R02 from Novus Biologicals
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ATP4B - MBS8225266 from MyBioSource
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shRNA set against Human ATP4B (NM_000705.3) - SHH242722 from Creative biogene
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Human ATP4B siRNA - orb260851 from Biorbyt
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ATP4B shRNA Plasmid (Human) - CHH0349 from Cohesion Biosciences
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ATP4B miRNA 3'UTR clone - MiUTR3H-00859 from Creative biogene
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