Gene Symbol | PARP4 |
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Entrez Gene | 143 |
Alt Symbol | ADPRTL1, ARTD4, PARP-4, PARPL, PH5P, VAULT3, VPARP, VWA5C, p193 |
Species | Human |
Gene Type | protein-coding |
Description | poly (ADP-ribose) polymerase family, member 4 |
Other Description | 193 kDa vault protein|ADP-ribosyltransferase (NAD+; poly (ADP-ribose) polymerase)-like 1|ADP-ribosyltransferase diphtheria toxin-like 4|H5 proline-rich|I-alpha-I-related|PARP-related|PARP-related/IalphaI-related H5/proline-rich|poly [ADP-ribose] polymerase 4|poly(ADP-ribose) synthetase|poly(ADP-ribosyl)transferase-like 1|vault poly(ADP-ribose) polymerase|vault protein, 193-kDa|von Willebrand factor A domain containing 5C |
Swissprots | Q9UKK3 Q14682 Q9H1M6 O75903 Q5QNZ9 |
Accessions | EAX08336 Q9UKK3 AF057160 AAC62491 AF158255 AAD47250 AK304399 BAG65234 BC017815 AAH17815 BC167791 AAI67791 BX479127 CA308288 CV574448 D79999 BAA11494 DB238428 T10289 XM_011534931 XP_011533233 XM_011534932 XP_011533234 XR_941496 NM_006437 NP_006428 |
Subcellular Location | Cytoplasm. Nucleus. Cytoplasm, cytoskeleton, spindle. Note=Also found in the nucleus, associated with mitotic spindles. |
Tissue Specificity | Widely expressed; the highest levels are in the kidney; also detected in heart, placenta, lung, liver, skeletal muscle, spleen, leukocytes and pancreas. |
Top Pathways | Base excision repair |
PARP-4 CRISPR/Cas9 KO Plasmid (h) - sc-406615 from Santa Cruz Biotechnology
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PARP-4 HDR Plasmid (h) - sc-406615-HDR from Santa Cruz Biotechnology
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PARP-4 Double Nickase Plasmid (h) - sc-406615-NIC from Santa Cruz Biotechnology
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PARP-4 Double Nickase Plasmid (h2) - sc-406615-NIC-2 from Santa Cruz Biotechnology
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PARP-4 CRISPR Activation Plasmid (h) - sc-406615-ACT from Santa Cruz Biotechnology
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PARP-4 CRISPR Activation Plasmid (h2) - sc-406615-ACT-2 from Santa Cruz Biotechnology
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PARP-4 Lentiviral Activation Particles (h) - sc-406615-LAC from Santa Cruz Biotechnology
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PARP-4 Lentiviral Activation Particles (h2) - sc-406615-LAC-2 from Santa Cruz Biotechnology
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PARP-4 siRNA (h) - sc-61299 from Santa Cruz Biotechnology
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PARP-4 shRNA Plasmid (h) - sc-61299-SH from Santa Cruz Biotechnology
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PARP-4 shRNA (h) Lentiviral Particles - sc-61299-V from Santa Cruz Biotechnology
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PARP4 RNAi - H00000143-R01 from Novus Biologicals
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CompoZr® Knockout ZFN Kit - CKOZFN16350 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND16350 from Sigma-Aldrich
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PARP4 siRNA (Human) - CRH0100 from Cohesion Biosciences
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PARP-4 CRISPR/Cas9 KO Plasmid (h2) - sc-406615-KO-2 from Santa Cruz Biotechnology
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PARP-4 HDR Plasmid (h2) - sc-406615-HDR-2 from Santa Cruz Biotechnology
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shRNA set against Human PARP4(NM_006437.3) - SHR088818 from Creative biogene
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Human PARP4 siRNA - orb260602 from Biorbyt
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PARP4 shRNA Plasmid (Human) - CHH0100 from Cohesion Biosciences
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PARP4 miRNA 3'UTR clone - MiUTR1H-07526 from Creative biogene
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