PARP4

Gene Symbol PARP4
Entrez Gene 143
Alt Symbol ADPRTL1, ARTD4, PARP-4, PARPL, PH5P, VAULT3, VPARP, VWA5C, p193
Species Human
Gene Type protein-coding
Description poly (ADP-ribose) polymerase family, member 4
Other Description 193 kDa vault protein|ADP-ribosyltransferase (NAD+; poly (ADP-ribose) polymerase)-like 1|ADP-ribosyltransferase diphtheria toxin-like 4|H5 proline-rich|I-alpha-I-related|PARP-related|PARP-related/IalphaI-related H5/proline-rich|poly [ADP-ribose] polymerase 4|poly(ADP-ribose) synthetase|poly(ADP-ribosyl)transferase-like 1|vault poly(ADP-ribose) polymerase|vault protein, 193-kDa|von Willebrand factor A domain containing 5C
Swissprots Q9UKK3 Q14682 Q9H1M6 O75903 Q5QNZ9
Accessions EAX08336 Q9UKK3 AF057160 AAC62491 AF158255 AAD47250 AK304399 BAG65234 BC017815 AAH17815 BC167791 AAI67791 BX479127 CA308288 CV574448 D79999 BAA11494 DB238428 T10289 XM_011534931 XP_011533233 XM_011534932 XP_011533234 XR_941496 NM_006437 NP_006428
Subcellular Location Cytoplasm. Nucleus. Cytoplasm, cytoskeleton, spindle. Note=Also found in the nucleus, associated with mitotic spindles.
Tissue Specificity Widely expressed; the highest levels are in the kidney; also detected in heart, placenta, lung, liver, skeletal muscle, spleen, leukocytes and pancreas.
Top Pathways Base excision repair

PARP-4 (A-18) - sc-49474 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
PARP-4 (A-18): sc-49474. Western blot analysis of PARP-4 expression in HeLa (A) and UV treated HeLa (B) whole cell lysates and UV treated HeLa nuclear extract (C).

PARP-4 (E-19) - sc-49475 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Anti-PARP4 antibody - ab86066 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) analysis of human colon carcinoma tissue labelling PARP4 with ab86066 at 1/200 (1µg/ml). Detection: DAB.

Anti-PARP4 antibody - ab200362 from Abcam

Prices $359.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemical analysis of paraffin-embedded Human prostate cancer tissue labeling PARP4 with ab200362 at 1/20 dilution.

Anti-PARP4 antibody - ab111737 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
ab111737 at 1/50 dilution staining PARP4 in paraffin-embedded Human Breast carcinoma tissue by Immunohistochemistry. Left panel shows staining without immunizing peptide right panel shows staining with immunizing peptide.

Anti-PARP4 antibody [EPR8230] - ab133745 from Abcam

Prices $313.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR8230
All lanes : Anti-PARP4 antibody [EPR8230] (ab133745) at 1/1000 dilutionLane 1 : HeLa cell lysate at 10 µgLane 2 : HepG2 cell lysate at 10 µgLane 3 : Human fetal kidney tissue lysateLane 4 : 293T cell lysate at 10 µgLane 5 : Human fetal liver tissue lysateSecondaryGoat anti-Rabbit HRP at 1/2000 dilution

Anti-PARP4 antibody [P193-10] - ab24110 from Abcam

Prices $370.00
Sizes 500 µl
Host Mouse
Clonality Monoclonal
Clone P193-10
IHC image of PARP4 staining in human kidney formalin fixed paraffin embedded tissue section, performed on a Leica Bond system using the standard protocol F. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH6, epitope retrieval solution 1) for 20 mins. The section was then incubated with ab24110, 10µg/ml, for 15 mins at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX.For other IHC staining systems (automated and non-automated) customers should optimize variable parameters such as antigen retrieval conditions, primary antibody concentration and antibody incubation times.

Anti-PARP4 antibody [p193-4] - ab50215 from Abcam

Host Mouse
Clonality Monoclonal
Clone p193-4

Anti-PARP4 / VPARP Antibody (aa506-510) - LS-C9068 from LifeSpan Bioscience

Prices $445.00
Sizes 125 µg
Host Mouse
Clonality Monoclonal

Anti-PARP4 / VPARP Antibody (aa408-611, clone P193-10) - LS-C124132 from LifeSpan Bioscience

Prices $665.00
Sizes 1 ml
Host Mouse
Clonality Monoclonal
Clone P193-10

Anti-PARP4 / VPARP Antibody (aa408-611, clone P193-4) - LS-C124133 from LifeSpan Bioscience

Prices $665.00
Sizes 1 ml
Host Mouse
Clonality Monoclonal
Clone P193-4

Anti-PARP4 / VPARP Antibody (aa408-611, clone P193-6) - LS-C124134 from LifeSpan Bioscience

Prices $665.00
Sizes 1 ml
Host Mouse
Clonality Monoclonal
Clone P193-6

Anti-PARP4 / VPARP Antibody (N-Terminus) - LS-C125958 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Mouse
Clonality Monoclonal

Anti-PARP4 / VPARP Antibody (aa1151-1200) - LS-C119584 from LifeSpan Bioscience

Prices $315.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
IHC of paraffin-embedded human breast carcinoma, using PARP4 Antibody. The picture on the right is treated with the synthesized peptide.

Anti-PARP4 / VPARP Antibody (clone 2695C5a) - LS-C184713 from LifeSpan Bioscience

Prices $335.00
Sizes 50 µg
Host Mouse
Clonality Monoclonal
Clone 2695C5a

Anti-PARP4 / VPARP Antibody (clone P193-10) - LS-C202622 from LifeSpan Bioscience

Prices $325.00
Sizes 1 ml
Host Mouse
Clonality Monoclonal
Clone P193-10

Anti-PARP4 / VPARP Antibody (clone P193-4) - LS-C202623 from LifeSpan Bioscience

Prices $325.00
Sizes 1 ml
Host Mouse
Clonality Monoclonal
Clone P193-4

Anti-PARP4 / VPARP Antibody (clone P193-6) - LS-C202624 from LifeSpan Bioscience

Prices $325.00
Sizes 1 ml
Host Mouse
Clonality Monoclonal
Clone P193-6

Anti-PARP4 / VPARP Antibody (aa1400-1450) - LS-C286098 from LifeSpan Bioscience

Prices $375.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-PARP4 / VPARP Antibody (C-Terminus, clone EPR8230) - LS-C154506 from LifeSpan Bioscience

Prices $395.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR8230
Western blot analysis on (A) HeLa, (B) HepG2, (C) fetal kidney, (D) 293T, and (E) fetal liver lysates using anti-PARP4 antibody.

Anti-PARP4 / VPARP Antibody (aa1674-1724) - LS-C286099 from LifeSpan Bioscience

Prices $375.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Detection of Human vPARP by Immunohistochemistry. Sample: FFPE section of human colon carcinoma. Antibody: Affinity purified rabbit anti-vPARP used at a dilution of 1:200 (1 ug/ml). Detection: DAB.

Anti-PARP4 / VPARP Antibody (aa1674-1724) - LS-C286791 from LifeSpan Bioscience

Prices $415.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Detection of Human vPARP by Immunohistochemistry. Sample: FFPE section of human ovarian carcinoma. Antibody: Affinity purified rabbit anti-vPARP used at a dilution of 1:250.

Anti-PARP4 / VPARP Antibody (clone 2695C5a) - LS-C342862 from LifeSpan Bioscience

Prices $375.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 2695C5a
Immunostaining analysis in HeLa cells. HeLa cells were fixed with 4% paraformaldehyde and permeabilized with 0.1% Triton X-100 in PBS. The cells were immunostained with anti-PARP4 mAb.

PARP4 Antibody - NBP1-06563 from Novus Biologicals

Prices $359.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: PARP4 Antibody [NBP1-06563] - Whole cell lysate from HeLa cells. vPARP was also immunoprecipitated by rabbit anti-vPARP antibody NBP1-06562, which recognizes an upstream epitope.

PARP4 Antibody - NBP1-89232 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: PARP4 Antibody [NBP1-89232] - Lane 1: Marker [kDa] 230, 130, 95, 72, 56, 36, 28, 17, 11. Lane 2: Human cell line RT-4. Lane 3: Human cell line U-251MG sp
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