| Gene Symbol |
Bcl11b
|
| Entrez Gene |
58208
|
| Alt Symbol |
9130430L19Rik, AI604821, B630002E05Rik, BCL-11B, Ctip2, Rit1
|
| Species |
Mouse
|
| Gene Type |
protein-coding
|
| Description |
B cell leukemia/lymphoma 11B
|
| Other Description |
B-cell CLL/lymphoma 11B|B-cell leukemia/lymphoma 11B|B-cell lymphoma/leukaemia 11B|B-cell lymphoma/leukemia 11B|COUP-TF interacting protein 2|COUP-TF-interacting protein 2|mRit1|radiation-induced tumor suppressor gene 1 protein
|
| Swissprots |
Q9JLF8 Q8C2I1 Q99PV8 Q99PV7 Q99PV6
|
| Accessions |
EDL18728 EDL18729 Q99PV8 AB043551 BAB32728 AB043553 BAB32729 AB043583 BAB32730 AF186019 AAF63683 AK020296 AK080974 AK088219 AK088588 BAC40438 AK140184 AK169655 BAE41279 BC019503 AAH19503 BM950501 BQ442983 BQ745012 CV563304 XM_006516110 XP_006516173 XM_006516111 XP_006516174 XM_006516113 XP_006516176 XM_006516114 XP_006516177 XM_006516115 XP_006516178 XM_006516116 XP_006516179 XM_011244152 XP_011242454 XM_011244153 XP_011242455 NM_001079883 NP_001073352 NM_001286343 NP_001273272 NM_021399 NP_067374
|
| Function |
Tumor-suppressor protein involved in T-cell lymphomas. May function on the P53-signaling pathway. May be a key regulator of both differentiation and survival during thymocyte development. Repress transcription through direct, TFCOUP2-independent binding to a GC-rich response element. {ECO:0000269|PubMed:12717433}.
|
| Subcellular Location |
Nucleus {ECO:0000305}.
|
| Tissue Specificity |
Expressed in brain and thymus.
|
