| Gene Symbol |
PPP6R1
|
| Entrez Gene |
22870
|
| Alt Symbol |
KIAA1115, PP6R1, SAP190, SAPS1
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
protein phosphatase 6, regulatory subunit 1
|
| Other Description |
SAPS domain family, member 1|serine/threonine-protein phosphatase 6 regulatory subunit 1
|
| Swissprots |
Q9BU97 Q6NVJ6 Q504V2 Q9UPN7 Q2M2H3
|
| Accessions |
EAW72352 EAW72353 EAW72354 Q9UPN7 AB029038 BAA83067 AK126810 AK297152 BAG59651 AL544921 BC002799 AAH02799 BC007629 AAH07629 BC068014 AAH68014 BC094753 AAH94753 BC111980 BC113443 BG772019 BX362839 NM_014931 NP_055746
|
| Function |
Regulatory subunit of protein phosphatase 6 (PP6). May function as a scaffolding PP6 subunit. Involved in the PP6- mediated dephosphorylation of NFKBIE opposing its degradation in response to TNF-alpha. {ECO:0000269|PubMed:16769727}.
|
| Subcellular Location |
Cytoplasm {ECO:0000269|PubMed:16769727, ECO:0000269|PubMed:18186651}.
|
| Tissue Specificity |
Ubiquitous with higher expression in testis. {ECO:0000269|PubMed:16769727}.
|