| Gene Symbol |
ERC2
|
| Entrez Gene |
26059
|
| Alt Symbol |
CAST, CAST1, ELKSL, SPBC110, Spc110
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
ELKS/RAB6-interacting/CAST family member 2
|
| Other Description |
CAZ-associated structural protein|ERC protein 2|cytomatrix protein p110
|
| Swissprots |
Q2T9F6 O15083 Q86TK4
|
| Accessions |
EAW65315 EAW65316 O15083 AB002376 BAA20832 BC060881 BC068563 BC094783 BC111550 AAI11551 BC112391 AAI12392 XM_011533580 XP_011531882 XM_011533581 XP_011531883 XM_011533582 XP_011531884 XR_245112 XR_245114 NM_015576 NP_056391
|
| Function |
Thought to be involved in the organization of the cytomatrix at the nerve terminals active zone (CAZ) which regulates neurotransmitter release. Seems to act together with BSN. May recruit liprin-alpha proteins to the CAZ.
|
| Subcellular Location |
Cytoplasm {ECO:0000269|PubMed:12923177}. Cell junction, synapse {ECO:0000269|PubMed:12923177}. Cell junction, synapse, synaptosome {ECO:0000269|PubMed:12923177}. Cytoplasm, cytoskeleton {ECO:0000269|PubMed:12923177}. Note=In neurons, localized to synapses, and colocalizes with PCLO. Localized to the active zone of presynaptic density (By similarity). {ECO:0000250}.
|