| Gene Symbol |
SLC9A6
|
| Entrez Gene |
10479
|
| Alt Symbol |
MRSA, NHE6
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
solute carrier family 9, subfamily A (NHE6, cation proton antiporter 6), member 6
|
| Other Description |
Na(+)/H(+) exchanger 6|sodium/hydrogen exchanger 6|solute carrier family 9 (sodium/hydrogen exchanger), member 6
|
| Swissprots |
Q5JPP9 B7ZAE0 Q3ZCW7 Q5JPP8 B4DU30 A6NIQ9 A8K160 Q86VS0 Q92581
|
| Accessions |
EAW88481 EAW88482 Q92581 AB074255 BAB72002 AF030409 AAC39643 AK289775 BAF82464 AK296444 BAG59095 AK297218 BAG59701 AK300475 BAG62192 AK314562 AK316255 BAH14626 BC035029 AAH35029 BC047375 BC049169 AAH49169 D87743 BAA13449 DB483081 DC308430 R15803 XM_006724726 XP_006724789 XM_011531243 XP_011529545 NM_001042537 NP_001036002 NM_001177651 NP_001171122 NM_006359 NP_006350
|
| Function |
Electroneutral exchange of protons for Na(+) and K(+) across the early and recycling endosome membranes. Contributes to calcium homeostasis.
|
| Subcellular Location |
Endosome membrane {ECO:0000269|PubMed:11940519}; Multi-pass membrane protein {ECO:0000269|PubMed:11940519}. Note=Is present in the recycling compartments including early and recycling endosomes, and only appears transiently on the plasma membrane.
|
| Tissue Specificity |
Ubiquitous; but is most abundant in mitochondrion-rich tissues such as brain, skeletal muscle and heart.
|
| Top Pathways |
Cardiac muscle contraction
|