Gene Symbol | SLC9A6 |
---|---|
Entrez Gene | 10479 |
Alt Symbol | MRSA, NHE6 |
Species | Human |
Gene Type | protein-coding |
Description | solute carrier family 9, subfamily A (NHE6, cation proton antiporter 6), member 6 |
Other Description | Na(+)/H(+) exchanger 6|sodium/hydrogen exchanger 6|solute carrier family 9 (sodium/hydrogen exchanger), member 6 |
Swissprots | Q5JPP9 B7ZAE0 Q3ZCW7 Q5JPP8 B4DU30 A6NIQ9 A8K160 Q86VS0 Q92581 |
Accessions | EAW88481 EAW88482 Q92581 AB074255 BAB72002 AF030409 AAC39643 AK289775 BAF82464 AK296444 BAG59095 AK297218 BAG59701 AK300475 BAG62192 AK314562 AK316255 BAH14626 BC035029 AAH35029 BC047375 BC049169 AAH49169 D87743 BAA13449 DB483081 DC308430 R15803 XM_006724726 XP_006724789 XM_011531243 XP_011529545 NM_001042537 NP_001036002 NM_001177651 NP_001171122 NM_006359 NP_006350 |
Function | Electroneutral exchange of protons for Na(+) and K(+) across the early and recycling endosome membranes. Contributes to calcium homeostasis. |
Subcellular Location | Endosome membrane {ECO:0000269|PubMed:11940519}; Multi-pass membrane protein {ECO:0000269|PubMed:11940519}. Note=Is present in the recycling compartments including early and recycling endosomes, and only appears transiently on the plasma membrane. |
Tissue Specificity | Ubiquitous; but is most abundant in mitochondrion-rich tissues such as brain, skeletal muscle and heart. |
Top Pathways | Cardiac muscle contraction |
NHE-6 CRISPR/Cas9 KO Plasmid (h) - sc-404829 from Santa Cruz Biotechnology
|
||||||||
NHE-6 HDR Plasmid (h) - sc-404829-HDR from Santa Cruz Biotechnology
|
||||||||
NHE-6 Double Nickase Plasmid (h) - sc-404829-NIC from Santa Cruz Biotechnology
|
||||||||
NHE-6 Double Nickase Plasmid (h2) - sc-404829-NIC-2 from Santa Cruz Biotechnology
|
||||||||
NHE-6 CRISPR Activation Plasmid (h) - sc-404829-ACT from Santa Cruz Biotechnology
|
||||||||
NHE-6 CRISPR Activation Plasmid (h2) - sc-404829-ACT-2 from Santa Cruz Biotechnology
|
||||||||
NHE-6 Lentiviral Activation Particles (h) - sc-404829-LAC from Santa Cruz Biotechnology
|
||||||||
NHE-6 Lentiviral Activation Particles (h2) - sc-404829-LAC-2 from Santa Cruz Biotechnology
|
||||||||
NHE-6 siRNA (h) - sc-42658 from Santa Cruz Biotechnology
|
||||||||
NHE-6 shRNA Plasmid (h) - sc-42658-SH from Santa Cruz Biotechnology
|
||||||||
NHE-6 shRNA (h) Lentiviral Particles - sc-42658-V from Santa Cruz Biotechnology
|
||||||||
MISSION® esiRNA - EHU101331 from Sigma-Aldrich
|
||||||||
CompoZr® Knockout ZFN Kit - CKOZFN1888 from Sigma-Aldrich
|
||||||||
CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND1888 from Sigma-Aldrich
|
||||||||
MISSION® 3′UTR Lenti GoClone™ - HUTR11552 from Sigma-Aldrich
|
||||||||
SLC9A6 siRNA (Human) - CRH7116 from Cohesion Biosciences
|
||||||||
SLC9A6 - MBS8240582 from MyBioSource
|
||||||||
shRNA set against Human SLC9A6 (NM_006359.2) - SHH412356 from Creative biogene
|
||||||||
shRNA set against Human SLC9A6(NM_001042537.1) - SHL012806 from Creative biogene
|
||||||||
shRNA set against Human SLC9A6(NM_006359.2) - SHL012960 from Creative biogene
|
||||||||
NHE-6 CRISPR/Cas9 KO Plasmid (h2) - sc-404829-KO-2 from Santa Cruz Biotechnology
|
||||||||
NHE-6 HDR Plasmid (h2) - sc-404829-HDR-2 from Santa Cruz Biotechnology
|
||||||||
Human SLC9A6 siRNA - orb267618 from Biorbyt
|
||||||||
SLC9A6 shRNA Plasmid (Human) - CHH7116 from Cohesion Biosciences
|
||||||||
SLC9A6 miRNA 3'UTR clone - MiUTR1H-09611 from Creative biogene
|