| Gene Symbol |
GRK7
|
| Entrez Gene |
131890
|
| Alt Symbol |
GPRK7
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
G protein-coupled receptor kinase 7
|
| Other Description |
g protein-coupled receptor kinase GRK7
|
| Swissprots |
Q8WTQ7
|
| Accessions |
EAW78990 Q8WTQ7 AF282269 AAL33880 AF439409 AAL48216 BC148327 AAI48328 BC152977 AAI52978 DQ426875 XM_011512434 XP_011510736 NM_139209 NP_631948
|
| Function |
Retina-specific kinase involved in the shutoff of the photoresponse and adaptation to changing light conditions via cone opsin phosphorylation, including rhodopsin (RHO). {ECO:0000269|PubMed:15946941}.
|
| Subcellular Location |
Membrane {ECO:0000250|UniProtKB:Q8WMV0}; Lipid-anchor {ECO:0000250|UniProtKB:Q8WMV0}.
|
| Tissue Specificity |
Retinal cones, outer and inner segments. {ECO:0000269|PubMed:11754336, ECO:0000269|PubMed:18803695}.
|
| Top Pathways |
Endocytosis, Chemokine signaling pathway, Phototransduction
|