Gene Symbol | GRK7 |
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Entrez Gene | 131890 |
Alt Symbol | GPRK7 |
Species | Human |
Gene Type | protein-coding |
Description | G protein-coupled receptor kinase 7 |
Other Description | g protein-coupled receptor kinase GRK7 |
Swissprots | Q8WTQ7 |
Accessions | EAW78990 Q8WTQ7 AF282269 AAL33880 AF439409 AAL48216 BC148327 AAI48328 BC152977 AAI52978 DQ426875 XM_011512434 XP_011510736 NM_139209 NP_631948 |
Function | Retina-specific kinase involved in the shutoff of the photoresponse and adaptation to changing light conditions via cone opsin phosphorylation, including rhodopsin (RHO). {ECO:0000269|PubMed:15946941}. |
Subcellular Location | Membrane {ECO:0000250|UniProtKB:Q8WMV0}; Lipid-anchor {ECO:0000250|UniProtKB:Q8WMV0}. |
Tissue Specificity | Retinal cones, outer and inner segments. {ECO:0000269|PubMed:11754336, ECO:0000269|PubMed:18803695}. |
Top Pathways | Endocytosis, Chemokine signaling pathway, Phototransduction |
GRK 7 CRISPR/Cas9 KO Plasmid (h) - sc-407868 from Santa Cruz Biotechnology
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GRK 7 HDR Plasmid (h) - sc-407868-HDR from Santa Cruz Biotechnology
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GRK 7 Double Nickase Plasmid (h) - sc-407868-NIC from Santa Cruz Biotechnology
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GRK 7 Double Nickase Plasmid (h2) - sc-407868-NIC-2 from Santa Cruz Biotechnology
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GRK 7 CRISPR Activation Plasmid (h) - sc-407868-ACT from Santa Cruz Biotechnology
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GRK 7 CRISPR Activation Plasmid (h2) - sc-407868-ACT-2 from Santa Cruz Biotechnology
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GRK 7 Lentiviral Activation Particles (h) - sc-407868-LAC from Santa Cruz Biotechnology
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GRK 7 Lentiviral Activation Particles (h2) - sc-407868-LAC-2 from Santa Cruz Biotechnology
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GRK 7 siRNA (h) - sc-60767 from Santa Cruz Biotechnology
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GRK 7 shRNA Plasmid (h) - sc-60767-SH from Santa Cruz Biotechnology
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GRK 7 shRNA (h) Lentiviral Particles - sc-60767-V from Santa Cruz Biotechnology
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GRK7 RNAi - H00131890-R02 from Novus Biologicals
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MISSION® siRNA - SIHK0863 from Sigma-Aldrich
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MISSION® siRNA - SIHK0865 from Sigma-Aldrich
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MISSION® siRNA - SIHK0864 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN9700 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND9700 from Sigma-Aldrich
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GRK7 siRNA (Human) - CRJ5077 from Cohesion Biosciences
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GRK7 - MBS827353 from MyBioSource
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shRNA set against Human GRK7 (NM_139209.2) - SHH308078 from Creative biogene
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Human GRK7 siRNA - orb275578 from Biorbyt
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GRK7 shRNA Plasmid (Human) - CHJ5077 from Cohesion Biosciences
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GRK7 miRNA 3'UTR clone - MiUTR1H-04288 from Creative biogene
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