| Gene Symbol |
TUBB2A
|
| Entrez Gene |
7280
|
| Alt Symbol |
CDCBM5, TUBB, TUBB2, dJ40E16.7
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
tubulin, beta 2A class IIa
|
| Other Description |
class IIa beta-tubulin|tubulin beta class IIa|tubulin beta-2A chain|tubulin, beta polypeptide 2
|
| Swissprots |
Q8IWR2 Q6FGZ8 Q13885
|
| Accessions |
EAW55124 Q13885 AK308772 AK312621 BAG35507 AL038778 AY159127 AAN85571 BC001194 AAH01194 BC018780 AAH18780 BC127873 BC141924 AAI41925 BC141925 AAI41926 CR541958 CAG46756 DQ892343 ABM83269 DQ895718 ABM86644 X79535 CAA56071 NM_001069 NP_001060
|
| Function |
Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain (By similarity). {ECO:0000250}.
|
| Subcellular Location |
Cytoplasm, cytoskeleton {ECO:0000250}.
|
| Tissue Specificity |
High expression in brain, where it represents 30% of all beta-tubulins. {ECO:0000269|PubMed:20191564}.
|
| Top Pathways |
Gap junction, Pathogenic Escherichia coli infection, Phagosome
|
![Western Blot: beta II Tubulin A Overexpression Lysate (Adult Normal) [NBL1-17437] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for beta II Tubulin A.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/6315_beta%2520II%2520Tubulin%2520A%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBL1-17437-img0003.jpg)