Gene Symbol | TUBB2A |
---|---|
Entrez Gene | 7280 |
Alt Symbol | CDCBM5, TUBB, TUBB2, dJ40E16.7 |
Species | Human |
Gene Type | protein-coding |
Description | tubulin, beta 2A class IIa |
Other Description | class IIa beta-tubulin|tubulin beta class IIa|tubulin beta-2A chain|tubulin, beta polypeptide 2 |
Swissprots | Q8IWR2 Q6FGZ8 Q13885 |
Accessions | EAW55124 Q13885 AK308772 AK312621 BAG35507 AL038778 AY159127 AAN85571 BC001194 AAH01194 BC018780 AAH18780 BC127873 BC141924 AAI41925 BC141925 AAI41926 CR541958 CAG46756 DQ892343 ABM83269 DQ895718 ABM86644 X79535 CAA56071 NM_001069 NP_001060 |
Function | Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain (By similarity). {ECO:0000250}. |
Subcellular Location | Cytoplasm, cytoskeleton {ECO:0000250}. |
Tissue Specificity | High expression in brain, where it represents 30% of all beta-tubulins. {ECO:0000269|PubMed:20191564}. |
Top Pathways | Gap junction, Pathogenic Escherichia coli infection, Phagosome |