SUMF1

Gene Symbol SUMF1
Entrez Gene 285362
Alt Symbol AAPA3037, FGE, UNQ3037
Species Human
Gene Type protein-coding
Description sulfatase modifying factor 1
Other Description C-alpha-formylglycine-generating enzyme 1|FGly-generating enzyme|sulfatase-modifying factor 1
Swissprots Q0VAC6 B4DXK5 Q2NL78 Q8NBK3 Q53ZE4 B7XD05 Q0VAC7 Q6UY39 G5E9B0 Q96AK5 E9PGL0 Q96DK8
Accessions CAH25965 EAW63906 EAW63907 Q8NBK3 AB448737 BAH11168 AK057983 BAB71625 AK075459 BAC11634 AK094111 AK295240 BAG58233 AK302018 BAG63417 AY208752 AAO34683 AY323910 AAP86217 AY358092 AAQ88459 BC017005 AAH17005 BC110862 AAI10863 BC121122 AAI21123 BC121123 AAI21124 BG705404 CA413741 DA844846 XM_011533623 XP_011531925 XM_011533624 XP_011531926 XM_011533625 XP_011531927 XM_011533626 XP_011531928 NM_001164674 NP_001158146 NM_001164675 NP_001158147 NM_182760 NP_877437
Function Using molecular oxygen and an unidentified reducing agent, oxidizes a cysteine residue in the substrate sulfatase to an active site 3-oxoalanine residue, which is also called C(alpha)-formylglycine. Known substrates include GALNS, ARSA, STS and ARSE. {ECO:0000269|PubMed:12757706, ECO:0000269|PubMed:15657036}.
Subcellular Location Endoplasmic reticulum lumen {ECO:0000269|PubMed:15657036, ECO:0000269|PubMed:15962010}.
Tissue Specificity Ubiquitous. Highly expressed in kidney, pancreas and liver. Detected at lower levels in leukocytes, lung, placenta, small intestine, skeletal muscle and heart. {ECO:0000269|PubMed:15962010}.
Top Pathways Lysosome

SUMF1 (A-4) - sc-374102 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
SUMF1 (A-4): sc-374102. Western blot analysis of SUMF1 expression in Caki-1 (A) and Hep G2 (B) whole cell lysates.

SUMF1 (C-19) - sc-82038 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

SUMF1 (B-9) - sc-376035 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
SUMF1 (B-9): sc-376035. Western blot analysis of SUMF1 expression in MIA PaCa-2 (A), Caki-1 (B), Hep G2 (C) and HeLa (D) whole cell lysates.

SUMF1 (H-131) - sc-98663 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal

SUMF1 (P-17) - sc-82040 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
SUMF1 (P-17): sc-82040. Western blot analysis of SUMF1 expression in Hep G2 (A), MIA PaCa-2 (B), HeLa (C), HEK293 (D) and K-562 (E) whole cell lysates.

Anti-SUMF1 antibody - ab103467 from Abcam

Prices $370.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Anti-SUMF1 antibody (ab103467) at 1/100 dilution + Hela cell line lysates at 35 µg

Anti-SUMF1 Antibody (aa310-339) - LS-C161611 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
SUMF1 Antibody immunohistochemistry of formalin-fixed and paraffin-embedded human pancreas tissue followed by peroxidase-conjugated secondary antibody and DAB staining.

Anti-SUMF1 Antibody (aa310-339, AP) - LS-C241419 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-SUMF1 Antibody (aa310-339, APC) - LS-C241420 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-SUMF1 Antibody (aa310-339, Biotin) - LS-C241421 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-SUMF1 Antibody (aa310-339, FITC) - LS-C241422 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-SUMF1 Antibody (aa310-339, PE) - LS-C241425 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-SUMF1 Antibody (aa310-339, Azide-free, HRP) - LS-C248284 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-SUMF1 Antibody (aa113-356, Biotin) - LS-C300429 from LifeSpan Bioscience

Prices $425.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-SUMF1 Antibody (aa113-356, FITC) - LS-C303313 from LifeSpan Bioscience

Prices $455.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-SUMF1 Antibody (aa292-341) - LS-C151647 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
SUMF1 antibody Western Blot of Fetal Liver.

Anti-SUMF1 Antibody (aa310-339) - LS-C325495 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-SUMF1 Antibody (Internal) - LS-C112861 from LifeSpan Bioscience

Prices $395.00
Sizes 100 µg
Host Goat
Clonality Polyclonal
SUMF1 antibody (1 ug/ml) staining of Mouse Pancreas lysate (35 ug protein/ml in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

Anti-SUMF1 Antibody (aa71-120) - LS-C187313 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Western blot of Human PANC1 Whole cell. SUMF1 antibody dilution 1.0 ug/ml.

Anti-SUMF1 Antibody (aa113-356) - LS-C296524 from LifeSpan Bioscience

Prices $405.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western blot of recombinant SUMF1.

Sulfatase Modifying Factor 1/SUMF1 Antibody (329005) - MAB2779 from Novus Biologicals

Prices $99.00, $249.00
Sizes 25 µg, 100 µg
Host Mouse
Clonality Monoclonal
Clone 329005

Sulfatase Modifying Factor 1/SUMF1 Antibody [Unconjugated] - AF3680 from Novus Biologicals

Prices $99.00, $359.00
Sizes 25 µg, 100 µg
Host Goat
Clonality Polyclonal
Western blot shows lysates of HepG2 human hepatocellular carcinoma cell line, Jurkat human acute T cell leukemia cell line, K562 human chronic myelogenous leukemia cell line, MCF‑7 human breast cancer cell line, and Raji human Burkitt's lymphoma cell line. PVDF membrane was probed with 1 µg/mL of Goat Anti-Human Sulfatase Modifying Factor 1/SUMF1 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF3680) followed by HRP-conjugated Anti-Goat IgG Secondary Antibody (Catalog # HAF019). Specific bands were detected for Sulfatase Modifying Factor 1/SUMF1 at approximately 40 and 55 kDa (as indicated). This experiment was conducted under reducing conditions and using Immunoblot Buffer Group 1.

Sulfatase Modifying Factor 1/SUMF1 Antibody - NBP1-83905 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: Sulfatase Modifying Factor 1/SUMF1 Antibody [NBP1-83905] - Lane 1: NIH-3T3 cell lysate (Mouse embryonic fibroblast cells). Lane 2: NBT-II cell lysate (Rat Wistar bladder tumor cells).

Sulfatase Modifying Factor 1/SUMF1 Antibody - NBP1-45212 from Novus Biologicals

Prices $329.00
Sizes 100 µg
Host Goat
Clonality Polyclonal
Western Blot: SUMF1 Antibody [NBP1-45212] - Analysis of SUMF1 in Mouse Pancreas lysate (35ug protein in RIPA buffer) using NBP1-45212 at 1ug/ml. Primary incubation was 1 hour. Detected by chemiluminescence.

SUMF1 Polyclonal Antibody - bs-12366R from Bioss

Prices $269.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
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