SUMF1

Gene Symbol	SUMF1
Entrez Gene	285362
Alt Symbol	AAPA3037, FGE, UNQ3037
Species	Human
Gene Type	protein-coding
Description	sulfatase modifying factor 1
Other Description	C-alpha-formylglycine-generating enzyme 1|FGly-generating enzyme|sulfatase-modifying factor 1
Swissprots	Q0VAC6 B4DXK5 Q2NL78 Q8NBK3 Q53ZE4 B7XD05 Q0VAC7 Q6UY39 G5E9B0 Q96AK5 E9PGL0 Q96DK8
Accessions	CAH25965 EAW63906 EAW63907 Q8NBK3 AB448737 BAH11168 AK057983 BAB71625 AK075459 BAC11634 AK094111 AK295240 BAG58233 AK302018 BAG63417 AY208752 AAO34683 AY323910 AAP86217 AY358092 AAQ88459 BC017005 AAH17005 BC110862 AAI10863 BC121122 AAI21123 BC121123 AAI21124 BG705404 CA413741 DA844846 XM_011533623 XP_011531925 XM_011533624 XP_011531926 XM_011533625 XP_011531927 XM_011533626 XP_011531928 NM_001164674 NP_001158146 NM_001164675 NP_001158147 NM_182760 NP_877437
Function	Using molecular oxygen and an unidentified reducing agent, oxidizes a cysteine residue in the substrate sulfatase to an active site 3-oxoalanine residue, which is also called C(alpha)-formylglycine. Known substrates include GALNS, ARSA, STS and ARSE. {ECO:0000269|PubMed:12757706, ECO:0000269|PubMed:15657036}.
Subcellular Location	Endoplasmic reticulum lumen {ECO:0000269|PubMed:15657036, ECO:0000269|PubMed:15962010}.
Tissue Specificity	Ubiquitous. Highly expressed in kidney, pancreas and liver. Detected at lower levels in leukocytes, lung, placenta, small intestine, skeletal muscle and heart. {ECO:0000269|PubMed:15962010}.
Top Pathways	Lysosome

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

SUMF1 CRISPR/Cas9 KO Plasmid (h) - sc-406543 from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

SUMF1 HDR Plasmid (h) - sc-406543-HDR from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

SUMF1 Double Nickase Plasmid (h) - sc-406543-NIC from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

SUMF1 Double Nickase Plasmid (h2) - sc-406543-NIC-2 from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

SUMF1 CRISPR Activation Plasmid (h) - sc-406543-ACT from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

SUMF1 CRISPR Activation Plasmid (h2) - sc-406543-ACT-2 from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

SUMF1 Lentiviral Activation Particles (h) - sc-406543-LAC from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

SUMF1 Lentiviral Activation Particles (h2) - sc-406543-LAC-2 from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

SUMF1 siRNA (h) - sc-76610 from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

SUMF1 shRNA Plasmid (h) - sc-76610-SH from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

SUMF1 shRNA (h) Lentiviral Particles - sc-76610-V from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

MISSION® esiRNA - EHU130421 from Sigma-Aldrich Category siRNA Prices $140.00, $250.00 Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN20829 from Sigma-Aldrich Category ZFN Kit Prices $4,999.00 Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND20829 from Sigma-Aldrich Category ZFN Kit Prices $3,999.00 Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR07527 from Sigma-Aldrich Category miRNA Prices $350.00 Sizes hutr07527

SUMF1 siRNA (Human) - CRJ7091 from Cohesion Biosciences Category siRNA Prices $340.00, $510.00 Sizes 15 nmol, 30 nmol Species Reactivities Human

SUMF1 - MBS8206508 from MyBioSource Prices $365.00, $515.00 Sizes 15 nmol, 30 nmol Species Reactivities Human

SUMF1 CRISPR/Cas9 KO Plasmid (h2) - sc-406543-KO-2 from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

SUMF1 HDR Plasmid (h2) - sc-406543-HDR-2 from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

shRNA set against Human SUMF1 (NM_182760.3) - SHH420876 from Creative biogene Category siRNA Species Reactivities Human

SUMF1 shRNA Plasmid (Human) - CHJ7091 from Cohesion Biosciences Category siRNA Prices $500.00, $750.00 Sizes 150 µg, 300 µg Species Reactivities Human

SUMF1 miRNA 3'UTR clone - MiUTR3H-09589 from Creative biogene Species Reactivities Human

SUMF1 miRNA 3'UTR clone - MiUTR3H-09590 from Creative biogene Species Reactivities Human

SUMF1 miRNA 3'UTR clone - MiUTR3H-09591 from Creative biogene Species Reactivities Human

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