| Gene Symbol |
CLDN6
|
| Entrez Gene |
9074
|
| Alt Symbol |
-
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
claudin 6
|
| Other Description |
claudin-6|skullin
|
| Swissprots |
D3DUA5 P56747 B3KQP9
|
| Accessions |
CAB56533 CAI72055 EAW85431 EAW85432 P56747 AF125306 AAK02013 AK075329 BAG52111 AY358480 AAQ88844 BC008934 AAH08934 BT007399 AAP36063 BX444798 CN420342 NM_021195 NP_067018
|
| Function |
Plays a major role in tight junction-specific obliteration of the intercellular space (By similarity). May act as a coreceptor for HCV entry into hepatic cells. {ECO:0000250, ECO:0000269|PubMed:17804490}.
|
| Subcellular Location |
Cell junction, tight junction {ECO:0000250}. Cell membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}.
|
| Tissue Specificity |
Expressed in the liver, in peripheral blood mononuclear cells and hepatocarcinoma cell lines. {ECO:0000269|PubMed:17804490}.
|
| Top Pathways |
Tight junction, Leukocyte transendothelial migration, Cell adhesion molecules (CAMs), Hepatitis C
|