Gene Symbol | MNDA |
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Entrez Gene | 4332 |
Alt Symbol | PYHIN3 |
Species | Human |
Gene Type | protein-coding |
Description | myeloid cell nuclear differentiation antigen |
Other Description | - |
Swissprots | P41218 |
Accessions | EAW52807 EAW52808 P41218 AK290392 BAF83081 AK313210 BAG36026 BC020715 AAH20715 BC032319 AAH32319 M81750 AAA69696 NM_002432 NP_002423 |
Function | May act as a transcriptional activator/repressor in the myeloid lineage. Plays a role in the granulocyte/monocyte cell- specific response to interferon. Stimulates the DNA binding of the transcriptional repressor protein YY1. |
Subcellular Location | Nucleus. Cytoplasm. Note=Uniformly distributed throughout the interphase cell nucleus. Associates with chromatin. |
Tissue Specificity | Expressed constitutively in cells of the myeloid lineage. Found in promyelocyte stage cells as well as in all other stage cells including peripheral blood monocytes and granulocytes. Also appear in myeloblast cells in some cases of acute myeloid Leukemia. {ECO:0000269|PubMed:8175894}. |
MNDA CRISPR/Cas9 KO Plasmid (h) - sc-406492 from Santa Cruz Biotechnology
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MNDA HDR Plasmid (h) - sc-406492-HDR from Santa Cruz Biotechnology
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MNDA Double Nickase Plasmid (h) - sc-406492-NIC from Santa Cruz Biotechnology
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MNDA Double Nickase Plasmid (h2) - sc-406492-NIC-2 from Santa Cruz Biotechnology
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MNDA CRISPR Activation Plasmid (h) - sc-406492-ACT from Santa Cruz Biotechnology
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MNDA CRISPR Activation Plasmid (h2) - sc-406492-ACT-2 from Santa Cruz Biotechnology
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MNDA Lentiviral Activation Particles (h) - sc-406492-LAC from Santa Cruz Biotechnology
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MNDA Lentiviral Activation Particles (h2) - sc-406492-LAC-2 from Santa Cruz Biotechnology
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MNDA siRNA (h) - sc-40701 from Santa Cruz Biotechnology
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MNDA shRNA Plasmid (h) - sc-40701-SH from Santa Cruz Biotechnology
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MNDA shRNA (h) Lentiviral Particles - sc-40701-V from Santa Cruz Biotechnology
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MNDA RNAi - H00004332-R01 from Novus Biologicals
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MISSION® esiRNA - EHU010951 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN14446 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND14446 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR02556 from Sigma-Aldrich
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MNDA siRNA (Human) - CRH2943 from Cohesion Biosciences
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shRNA set against Human MNDA (NM_002432.1) - SHH343220 from Creative biogene
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shRNA set against Human MNDA(NM_002432.1) - SHH194537 from Creative biogene
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Human MNDA siRNA - orb263445 from Biorbyt
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MNDA shRNA Plasmid (Human) - CHH2943 from Cohesion Biosciences
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MNDA miRNA 3'UTR clone - MiUTR1H-06366 from Creative biogene
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