Gene Symbol |
ZNF645
|
Entrez Gene |
158506
|
Alt Symbol |
CT138, HAKAIL
|
Species |
Human
|
Gene Type |
protein-coding
|
Description |
zinc finger protein 645
|
Other Description |
E3 ubiquitin ligase|E3 ubiquitin-protein ligase ZNF645
|
Swissprots |
A0AV29 A0AV31 Q8N7E2 E3SBK4 Q6DJY9
|
Accessions |
CBH30759 EAW98989 Q8N7E2 AK098601 BAC05348 BC074910 AAH74910 BC126190 AAI26191 BC126192 AAI26193 BX103567 GQ355336 ADI56589 HQ258412 ADR83166 HQ258552 ADR83306 NM_152577 NP_689790
|
Function |
E3 ubiquitin ligase catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins. May operate on tyrosine-phosphorylated SRC substrates. {ECO:0000269|PubMed:22252131}.
|
Subcellular Location |
Cytoplasm {ECO:0000269|PubMed:20657603}. Note=Localized over the postacrosomal perinuclear theca region and the entire length of sperm tail.
|
Tissue Specificity |
Exclusively expressed in testis and sperm, including spermatocytes, round and elongated spermatids, and Leydig cells. {ECO:0000269|PubMed:20657603}.
|