Gene Symbol | ZNF645 |
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Entrez Gene | 158506 |
Alt Symbol | CT138, HAKAIL |
Species | Human |
Gene Type | protein-coding |
Description | zinc finger protein 645 |
Other Description | E3 ubiquitin ligase|E3 ubiquitin-protein ligase ZNF645 |
Swissprots | A0AV29 A0AV31 Q8N7E2 E3SBK4 Q6DJY9 |
Accessions | CBH30759 EAW98989 Q8N7E2 AK098601 BAC05348 BC074910 AAH74910 BC126190 AAI26191 BC126192 AAI26193 BX103567 GQ355336 ADI56589 HQ258412 ADR83166 HQ258552 ADR83306 NM_152577 NP_689790 |
Function | E3 ubiquitin ligase catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins. May operate on tyrosine-phosphorylated SRC substrates. {ECO:0000269|PubMed:22252131}. |
Subcellular Location | Cytoplasm {ECO:0000269|PubMed:20657603}. Note=Localized over the postacrosomal perinuclear theca region and the entire length of sperm tail. |
Tissue Specificity | Exclusively expressed in testis and sperm, including spermatocytes, round and elongated spermatids, and Leydig cells. {ECO:0000269|PubMed:20657603}. |
ZNF645 CRISPR/Cas9 KO Plasmid (h) - sc-414793 from Santa Cruz Biotechnology
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ZNF645 HDR Plasmid (h) - sc-414793-HDR from Santa Cruz Biotechnology
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ZNF645 Double Nickase Plasmid (h) - sc-414793-NIC from Santa Cruz Biotechnology
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ZNF645 Double Nickase Plasmid (h2) - sc-414793-NIC-2 from Santa Cruz Biotechnology
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ZNF645 CRISPR Activation Plasmid (h) - sc-414793-ACT from Santa Cruz Biotechnology
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ZNF645 CRISPR Activation Plasmid (h2) - sc-414793-ACT-2 from Santa Cruz Biotechnology
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ZNF645 Lentiviral Activation Particles (h) - sc-414793-LAC from Santa Cruz Biotechnology
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ZNF645 Lentiviral Activation Particles (h2) - sc-414793-LAC-2 from Santa Cruz Biotechnology
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ZNF645 siRNA (h) - sc-91314 from Santa Cruz Biotechnology
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ZNF645 shRNA Plasmid (h) - sc-91314-SH from Santa Cruz Biotechnology
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ZNF645 shRNA (h) Lentiviral Particles - sc-91314-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU119711 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN23609 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND23609 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR01155 from Sigma-Aldrich
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ZNF645 siRNA (Human) - CRJ5865 from Cohesion Biosciences
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ZNF645 RNAi - H00158506-R01 from Novus Biologicals
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ZNF645 - MBS8225849 from MyBioSource
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shRNA set against Human ZNF645 (NM_152577.3) - SHH454740 from Creative biogene
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Human ZNF645 siRNA - orb276366 from Biorbyt
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ZNF645 shRNA Plasmid (Human) - CHJ5865 from Cohesion Biosciences
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ZNF645 miRNA 3'UTR clone - MiUTR4H-TG10344 from Creative biogene
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