Gene Symbol |
DRAM1
|
Entrez Gene |
55332
|
Alt Symbol |
DRAM
|
Species |
Human
|
Gene Type |
protein-coding
|
Description |
DNA-damage regulated autophagy modulator 1
|
Other Description |
DNA damage-regulated autophagy modulator protein 1|damage-regulated autophagy modulator
|
Swissprots |
Q8N682 Q9NUN1 B7Z4T0 Q7L3E3
|
Accessions |
EAW97685 EAW97686 Q8N682 AI079438 AK002121 BAA92091 AK094923 BAG52956 AK297785 BAH12666 BC013773 AAH13773 BC018435 AAH18435 DA721965 HQ447123 ADQ31610 XM_005269004 XP_005269061 XM_005269005 XP_005269062 XM_011538536 XP_011536838 NM_018370 NP_060840
|
Function |
Lysosomal modulator of autophagy that plays a central role in p53/TP53-mediated apoptosis. Not involved in p73/TP73- mediated autophagy. {ECO:0000269|PubMed:16839881, ECO:0000269|PubMed:17304243}.
|
Subcellular Location |
Lysosome membrane {ECO:0000269|PubMed:16839881}; Multi-pass membrane protein {ECO:0000269|PubMed:16839881}.
|