Gene Symbol |
SKAP2
|
Entrez Gene |
8935
|
Alt Symbol |
PRAP, RA70, SAPS, SCAP2, SKAP-HOM, SKAP55R
|
Species |
Human
|
Gene Type |
protein-coding
|
Description |
src kinase associated phosphoprotein 2
|
Other Description |
Fyn-associated phosphoprotein SKAP55 homologue|Pyk2/RAFTK-associated protein|SKAP-55HOM|SKAP55 homolog|retinoic acid-induced protein 70|src family-associated phosphoprotein 2|src kinase-associated phosphoprotein 2|src kinase-associated phosphoprotein of 55-related protein|src-associated adapter protein with PH and SH3 domains
|
Swissprots |
Q9UBZ3 O75563 Q75MZ4 Q9UED8 Q75MK6 A4D173 Q53GP6
|
Accessions |
AAS02033 AAS07536 EAL24231 EAW93858 EAW93859 EAW93860 O75563 AB014486 BAA36194 AF051323 AAC99296 AF072166 AAC39924 AF174049 AAD53795 AJ004886 CAA06193 AK222885 BAD96605 AK299216 BAH12970 AK299317 BAH12999 AK311454 AK313209 BAG36025 BC002893 AAH02893 BC036044 AAH36044 BI547092 BI826753 BQ433993 CA423048 DA714447 DA738803 DQ892896 ABM83822 DQ896144 ABM87143 HY044523 NM_001303468 NP_001290397 NM_003930 NP_003921
|
Function |
May be involved in B-cell and macrophage adhesion processes. In B-cells, may act by coupling the B-cell receptor (BCR) to integrin activation. May play a role in src signaling pathway. {ECO:0000269|PubMed:12893833, ECO:0000269|PubMed:9837776}.
|
Subcellular Location |
Cytoplasm {ECO:0000269|PubMed:12893833}.
|
Tissue Specificity |
Ubiquitously expressed. Present in platelets (at protein level). {ECO:0000269|PubMed:10942756, ECO:0000269|PubMed:9755858, ECO:0000269|PubMed:9837776}.
|