Gene Symbol | SKAP2 |
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Entrez Gene | 8935 |
Alt Symbol | PRAP, RA70, SAPS, SCAP2, SKAP-HOM, SKAP55R |
Species | Human |
Gene Type | protein-coding |
Description | src kinase associated phosphoprotein 2 |
Other Description | Fyn-associated phosphoprotein SKAP55 homologue|Pyk2/RAFTK-associated protein|SKAP-55HOM|SKAP55 homolog|retinoic acid-induced protein 70|src family-associated phosphoprotein 2|src kinase-associated phosphoprotein 2|src kinase-associated phosphoprotein of 55-related protein|src-associated adapter protein with PH and SH3 domains |
Swissprots | Q9UBZ3 O75563 Q75MZ4 Q9UED8 Q75MK6 A4D173 Q53GP6 |
Accessions | AAS02033 AAS07536 EAL24231 EAW93858 EAW93859 EAW93860 O75563 AB014486 BAA36194 AF051323 AAC99296 AF072166 AAC39924 AF174049 AAD53795 AJ004886 CAA06193 AK222885 BAD96605 AK299216 BAH12970 AK299317 BAH12999 AK311454 AK313209 BAG36025 BC002893 AAH02893 BC036044 AAH36044 BI547092 BI826753 BQ433993 CA423048 DA714447 DA738803 DQ892896 ABM83822 DQ896144 ABM87143 HY044523 NM_001303468 NP_001290397 NM_003930 NP_003921 |
Function | May be involved in B-cell and macrophage adhesion processes. In B-cells, may act by coupling the B-cell receptor (BCR) to integrin activation. May play a role in src signaling pathway. {ECO:0000269|PubMed:12893833, ECO:0000269|PubMed:9837776}. |
Subcellular Location | Cytoplasm {ECO:0000269|PubMed:12893833}. |
Tissue Specificity | Ubiquitously expressed. Present in platelets (at protein level). {ECO:0000269|PubMed:10942756, ECO:0000269|PubMed:9755858, ECO:0000269|PubMed:9837776}. |
SKAP55-R CRISPR/Cas9 KO Plasmid (h) - sc-418422 from Santa Cruz Biotechnology
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SKAP55-R HDR Plasmid (h) - sc-418422-HDR from Santa Cruz Biotechnology
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SKAP55-R Double Nickase Plasmid (h) - sc-418422-NIC from Santa Cruz Biotechnology
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SKAP55-R Double Nickase Plasmid (h2) - sc-418422-NIC-2 from Santa Cruz Biotechnology
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SKAP55-R CRISPR Activation Plasmid (h) - sc-418422-ACT from Santa Cruz Biotechnology
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SKAP55-R CRISPR Activation Plasmid (h2) - sc-418422-ACT-2 from Santa Cruz Biotechnology
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SKAP55-R Lentiviral Activation Particles (h) - sc-418422-LAC from Santa Cruz Biotechnology
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SKAP55-R Lentiviral Activation Particles (h2) - sc-418422-LAC-2 from Santa Cruz Biotechnology
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SKAP55-R siRNA (h) - sc-40600 from Santa Cruz Biotechnology
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SKAP55-R shRNA Plasmid (h) - sc-40600-SH from Santa Cruz Biotechnology
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SKAP55-R shRNA (h) Lentiviral Particles - sc-40600-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU024091 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN19377 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND19377 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR11715 from Sigma-Aldrich
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SKAP2 siRNA (Human) - CRH5909 from Cohesion Biosciences
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SCAP2 RNAi - H00008935-R02 from Novus Biologicals
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SKAP2 - MBS8238775 from MyBioSource
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shRNA set against Human SKAP2 (NM_003930.3) - SHH407948 from Creative biogene
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shRNA set against Human SKAP2(NM_003930.3) - SHR192804 from Creative biogene
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SKAP2 shRNA Plasmid (Human) - CHH5909 from Cohesion Biosciences
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SKAP2 miRNA 3'UTR clone - MiUTR1H-09420 from Creative biogene
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