Gene Symbol | KRTAP10-1 |
---|---|
Entrez Gene | 386677 |
Alt Symbol | KAP10.1, KAP18-1, KAP18.1, KRTAP10.1, KRTAP18-1, KRTAP18.1 |
Species | Human |
Gene Type | protein-coding |
Description | keratin associated protein 10-1 |
Other Description | high sulfur keratin-associated protein 10.1|keratin-associated protein 10-1|keratin-associated protein 10.1|keratin-associated protein 18-1|keratin-associated protein 18.1 |
Swissprots | Q0VAR0 P60331 Q0VAR1 |
Accessions | EAX09420 P60331 AB076347 BAD01534 AJ566380 CAD97461 BC120959 AAI20960 BC120960 AAI20961 NM_198691 NP_941964 |
Function | In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high- sulfur and high-glycine-tyrosine keratins. |
Tissue Specificity | Restricted to a narrow region of the hair fiber cuticle, lying approximately 20 cell layers above the apex of the dermal papilla of the hair root; not detected in any other tissues. {ECO:0000269|PubMed:14962103, ECO:0000269|PubMed:15028290}. |
KRTAP10-1 CRISPR/Cas9 KO Plasmid (h) - sc-408575 from Santa Cruz Biotechnology
|
||||||||
KRTAP10-1 HDR Plasmid (h) - sc-408575-HDR from Santa Cruz Biotechnology
|
||||||||
KRTAP10-1 Double Nickase Plasmid (h) - sc-408575-NIC from Santa Cruz Biotechnology
|
||||||||
KRTAP10-1 Double Nickase Plasmid (h2) - sc-408575-NIC-2 from Santa Cruz Biotechnology
|
||||||||
KRTAP10-1 CRISPR Activation Plasmid (h) - sc-408575-ACT from Santa Cruz Biotechnology
|
||||||||
KRTAP10-1 CRISPR Activation Plasmid (h2) - sc-408575-ACT-2 from Santa Cruz Biotechnology
|
||||||||
KRTAP10-1 Lentiviral Activation Particles (h) - sc-408575-LAC from Santa Cruz Biotechnology
|
||||||||
KRTAP10-1 Lentiviral Activation Particles (h2) - sc-408575-LAC-2 from Santa Cruz Biotechnology
|
||||||||
KRTAP10-1 siRNA (h) - sc-91521 from Santa Cruz Biotechnology
|
||||||||
KRTAP10-1 shRNA Plasmid (h) - sc-91521-SH from Santa Cruz Biotechnology
|
||||||||
KRTAP10-1 shRNA (h) Lentiviral Particles - sc-91521-V from Santa Cruz Biotechnology
|
||||||||
CompoZr® Knockout ZFN Kit - CKOZFN11414 from Sigma-Aldrich
|
||||||||
CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND11414 from Sigma-Aldrich
|
||||||||
KRTAP10-1 siRNA (Human) - CRJ7713 from Cohesion Biosciences
|
||||||||
shRNA set against Human KRTAP10-1(NM_198691.2) - SHH138503 from Creative biogene
|
||||||||
Human KRTAP10-1 siRNA - orb278214 from Biorbyt
|
||||||||
KRTAP10-1 shRNA Plasmid (Human) - CHJ7713 from Cohesion Biosciences
|
||||||||
KRTAP10-1 miRNA 3'UTR clone - MiUTR1H-05474 from Creative biogene
|
||||||||