| Gene Symbol |
Hnf1a
|
| Entrez Gene |
21405
|
| Alt Symbol |
AI323641, HNF1, HNF1-alpha, HNF1[a], Hnf-1, Hnf1alpha, LFB1, Tcf-1, Tcf1
|
| Species |
Mouse
|
| Gene Type |
protein-coding
|
| Description |
HNF1 homeobox A
|
| Other Description |
HNF-1-alpha|HNF-1A|hepatocyte nuclear factor 1|hepatocyte nuclear factor 1-alpha|liver-specific transcription factor LF-B1|transcription factor 1
|
| Swissprots |
E9QP86 P22361
|
| Accessions |
AAL86441 EDL19886 P22361 AK141225 AK142644 AK142677 AK144051 BC013454 BC080698 AAH80698 M57966 AAA37821 XM_011248192 XP_011246494 NM_009327 NP_033353
|
| Function |
Transcriptional activator that regulates the tissue specific expression of multiple genes, especially in pancreatic islet cells and in liver. Required for the expression of several liver specific genes. Binds to the inverted palindrome 5'- GTTAATNATTAAC-3'. {ECO:0000269|PubMed:10966642, ECO:0000269|PubMed:19289501}.
|
| Subcellular Location |
Nucleus.
|
| Tissue Specificity |
Liver.
|
| Top Pathways |
Maturity onset diabetes of the young, Signaling pathways regulating pluripotency of stem cells
|