Gene Symbol | CAD |
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Entrez Gene | 790 |
Alt Symbol | - |
Species | Human |
Gene Type | protein-coding |
Description | carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase |
Other Description | CAD protein|CAD trifunctional protein|multifunctional protein CAD |
Swissprots | P27708 Q6P0Q0 Q96CK3 D6W552 |
Accessions | AAA51907 AAX93165 AAY24293 EAX00612 EAX00613 EAX00614 P27708 AB621827 BAK64162 AK226105 BC014178 AAH14178 BC065510 AAH65510 BG766243 BM927624 BQ447516 BU541191 BU558264 D78586 BAA11423 XM_005264555 XP_005264612 XM_005264556 XP_005264613 XM_005264557 XP_005264614 XM_005264558 XP_005264615 XM_006712101 XP_006712164 NM_001306079 NP_001293008 NM_004341 NP_004332 |
Function | This protein is a "fusion" protein encoding four enzymatic activities of the pyrimidine pathway (GATase, CPSase, ATCase and DHOase). {ECO:0000269|PubMed:24332717}. |
Subcellular Location | Cytoplasm {ECO:0000269|PubMed:15890648}. Nucleus {ECO:0000269|PubMed:15890648}. Note=Cytosolic and unphosphorylated in resting cells, translocates to the nucleus in response to EGF stimulation, nuclear import promotes optimal cell growth. |
Top Pathways | Alanine, aspartate and glutamate metabolism, Pyrimidine metabolism |
CAD-Antibody-Center-Blocking-peptide - BP11110c from Abgent, a WuXi AppTec company
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CAD Protein Lysate (APL10451) - APL10451 from Aviva Systems Biology
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CAD Protein Lysate (APL10452) - APL10452 from Aviva Systems Biology
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CAD Protein Lysate (APL10726) - APL10726 from Aviva Systems Biology
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CAD Protein Lysate (APL10730) - APL10730 from Aviva Systems Biology
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CAD fusion protein - Ag9912 from Proteintech Group
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Recombinant Human CAD, His-tagged - CAD-10649H from Creative Biomart
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Recombinant Human CAD protein(CAD) ,partial - CSB-YP326741HU CSB-EP326741HU CSB-BP326741HU CSB-MP326741HU from Cusabio
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CAD Protein - abx163199 from Abbexa
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CAD protein (CAD), partial, Recombinant Protein - MBS1242190 from MyBioSource
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CAD Protein Lysate - orb333371 from Biorbyt
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CAD Protein Lysate - orb333498 from Biorbyt
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CAD Protein Lysate - orb333370 from Biorbyt
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CAD Protein Lysate - orb333497 from Biorbyt
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