Gene Symbol | KCNJ13 |
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Entrez Gene | 3769 |
Alt Symbol | KIR1.4, KIR7.1, LCA16, SVD |
Species | Human |
Gene Type | protein-coding |
Description | potassium channel, inwardly rectifying subfamily J, member 13 |
Other Description | inward rectifier K(+) channel Kir7.1|inward rectifier potassium channel 13|potassium inwardly-rectifying channel, subfamily J, member 13 |
Swissprots | Q53SA1 Q8N3Y4 O76023 A0PGH1 O60928 |
Accessions | AAD08673 AAX93190 EAW71019 O60928 AF061118 AAC15769 AJ006128 CAA06878 AJ007557 CAA07552 AK314019 BAG36730 AY758240 AAX08098 AY758241 AAX08099 BC037290 AAH37290 CB410257 DA278958 DB173405 DB547266 DN993097 DQ891724 ABM82650 DQ894901 ABM85827 NM_001172416 NP_001165887 NM_001172417 NP_001165888 NM_002242 NP_002233 |
Function | Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. KCNJ13 has a very low single channel conductance, low sensitivity to block by external barium and cesium, and no dependence of its inward rectification properties on the internal blocking particle magnesium. |
Subcellular Location | Membrane; Multi-pass membrane protein. |
Tissue Specificity | Predominantly expressed in small intestine. Expression is also detected in stomach, kidney, and all central nervous system regions tested with the exception of spinal cord. |
Top Pathways | Protein digestion and absorption |
KIR7.1 (C-12) - sc-398810 from Santa Cruz Biotechnology
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KIR7.1 (C-19) - sc-22440 from Santa Cruz Biotechnology
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KIR7.1 (N-16) - sc-22438 from Santa Cruz Biotechnology
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Anti-Kir7.1 antibody - ab81117 from Abcam
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Anti-KCNJ13 / KIR7.1 Antibody (aa74-103, Biotin) - LS-C246805 from LifeSpan Bioscience
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Anti-KCNJ13 / KIR7.1 Antibody (aa74-103, AP) - LS-C246803 from LifeSpan Bioscience
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Anti-KCNJ13 / KIR7.1 Antibody (aa200-250) - LS-C136627 from LifeSpan Bioscience
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Anti-KCNJ13 / KIR7.1 Antibody (aa74-103, FITC) - LS-C246806 from LifeSpan Bioscience
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Anti-KCNJ13 / KIR7.1 Antibody (aa74-103, Azide-free, HRP) - LS-C249305 from LifeSpan Bioscience
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Anti-KCNJ13 / KIR7.1 Antibody (aa74-103, PE) - LS-C246807 from LifeSpan Bioscience
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Anti-KCNJ13 / KIR7.1 Antibody (aa74-103, APC) - LS-C246804 from LifeSpan Bioscience
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Anti-KCNJ13 / KIR7.1 Antibody (aa74-103) - LS-C329717 from LifeSpan Bioscience
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Anti-KCNJ13 / KIR7.1 Antibody (aa67-95) IHC-plus⢠- LS-B10200 from LifeSpan Bioscience
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KCNJ13 Antibody - NBP1-20152 from Novus Biologicals
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KCNJ13 Antibody - NBP2-14143 from Novus Biologicals
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KCNJ13 Antibody - NBP2-27581 from Novus Biologicals
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ANTI-KCNJ13 (N-TERM) antibody produced in rabbit - SAB1301583 from Sigma-Aldrich
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Anti-KCNJ13 antibody produced in rabbit - HPA051609 from Sigma-Aldrich
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KCNJ13-Antibody-N-term - AP12387a from Abgent, a WuXi AppTec company
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Kir7.1 antibody - GTX53659 from GeneTex
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KCNJ13 Antibody - N-terminal region (OAAB08652) - OAAB08652 from Aviva Systems Biology
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KCNJ13 antibody - 70R-18078 from Fitzgerald
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Anti -KCNJ13 (ATP-Sensitive Inward Rectifier Potassium Channel 13, SVD, LCA16, KIR1.4,KIR7.1) - 211619 from USBiological Life Science
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Anti -KCNJ13 (KIR7.1, KIR7.1, LCA16, SVD, KIR1.4) - 215697 from USBiological Life Science
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Anti -KCNJ13, NT (KCNJ13, Inward rectifier potassium channel 13, Inward rectifier K(+)channel Kir7.1, Potassium channel, inwardly rectifying subfamily J member 13) - 037325 from USBiological Life Science
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